Malariya: Incamake hamwe nibikoresho byihuta byipimisha Byakozwe na Immune Colloidal Gold Technique

Malariya ni iki?

Malariya ni indwara yangiza ubuzima iterwa naPlasmodiumparasite, yanduza abantu binyuze mu kurumwa n’umugore wanduyeAnophelesimibu. Parasite ikurikira ubuzima bugoye: iyo binjiye mumubiri, babanza gutera ingirangingo z'umwijima kugwira, hanyuma bakarekura sporozoite yanduza selile zitukura. Mu maraso atukura, parasite yororoka vuba; iyo selile zimenetse, zirekura uburozi mumaraso, bigatera ibimenyetso bikomeye nko gukonja gutunguranye, umuriro mwinshi (akenshi ugera kuri 40 ° C), umunaniro, kandi mugihe gikomeye, kunanirwa kwingingo cyangwa gupfa.

Abana bari munsi yimyaka 5, abagore batwite, nabantu bafite intege nke z'umubiri bafite ibyago byinshi. Mugihe imiti igabanya ubukana nka chloroquine ikomeje kuba ingirakamaro mu kuvura, kwisuzumisha hakiri kare kandi neza ni urufunguzo rwo gucunga neza no kwirinda kwanduza. Ingamba zo kurwanya imibu (urugero, inshundura zo kuryama, udukoko twica udukoko) nazo zigira uruhare runini mu gukumira, ariko gutahura ku gihe bikomeje kuba urufatiro rwo kurwanya malariya.

Immune Colloidal Gold Technique: Guhindura Malariya Ibizamini Byihuse

Malariya yihuta yipimisha ibikoresho, harimo naMalariya Ag Pf / Pv Ikizamini cya Tri-umurongo, Malariya Ag Pf / Ikizamini cya Pan, Malariya Ag Pf / Pv / Pan Combo Test,Malariya Ag Pv Ikizamini Cassette, naMalariya Ag Pf Ikizamini Cassette, ubu koresha tekinike ya immun colloidal zahabu kugirango irusheho kuba nziza. Iri koranabuhanga ryagaragaye nkuburyo buyobora ibikoresho bya malariya byihuse bipimisha, hifashishijwe uduce duto twa zahabu twa colloidal twahujwe na antibodies kugirango tumenye antigene ya malariya mumaraso yose.

Uburyo Bikora

Ubuhanga bwa zahabu colloidal tekinike bukora ku ihame ryimikoranire ya antigen-antibody:

• Ibice bya zahabu bya colloidal (bifite ubunini bungana kuva kuri 24.8 kugeza 39.1 nm) bihujwe na antibodies yibasira antigene yihariye ya malariya (urugero, proteine ​​ikungahaye kuri histidine II kuriP. falciparum).
• Iyo icyitegererezo cyamaraso gishyizwe kuri cassette yipimisha, ibyo bikoresho bya zahabu-antibody bihuza na antigene iyo ari yo yose ya malariya ihari, ikora imirongo yamabara igaragara kumurongo wibizamini.

Ibyiza by'ingenzi

• Umuvuduko: Gutanga ibisubizo muminota 10-15, imirongo ibanza igaragara muminota 2.
• Ukuri: Kugera ku kumenya neza hafi 99%, kugabanya ibibi.
• Kumenya amoko menshi: Kumenya antigene kuva muri majoroPlasmodiumamoko, harimoP. falciparum, P. vivax, P. ovale, naP. malariya.
• Gukomera: Imikorere ihoraho mubice hamwe nicyitegererezo cyubwoko, hamwe nimbaraga ntoya yimbere, ndetse no mumikoro make.

Ibicuruzwa byacu Portfolio: Byashushanyije kubintu bitandukanye

Dutanga urutonde rwibikoresho bya malariya byihuse bishingiye ku buhanga bwa zahabu ikingira umubiri, byateguwe kugira ngo bikemurwe hakiri kare, kwipimisha mu rugo, no gusuzuma nini. Imbonerahamwe ikurikira irerekana muri make ibintu by'ingenzi:

Kwemeza Ivuriro rya Tri-umurongo Ibikoresho

Ubushakashatsi bwakozwe muri Tanzaniya bwasuzumye imikorere yubuvuzi bwa tri-line ukoresheje tekinike ya zahabu ikingira:

Porogaramu Hafi ya Scenarios

• Kurinda hakiri kare: Ibikoresho nka Malariya Ag Pv Ikizamini Cassette ifasha abantu mubice byugarijwe cyane no kumenya kwandura hakiri kare, bikarinda gutera indwara zikomeye.
• Kwipimisha murugo: Ibishushanyo mbonera byabakoresha (urugero, Malariya Ag Pf Ikizamini Cassette) ituma imiryango yipimisha nta mahugurwa yihariye, itanga ubufasha bwihuse.
• Igipimo kinini: Ibizamini bya Combo na pan-ubwoko (urugero, Malariya Ag Pf / Pv / Pan Combo Ikizamini) byorohereza ibizamini rusange mumashuri, aho bakorera, cyangwa mugihe cyadutse, bishyigikira ibintu byihuse.

Ibibazo

1.Ni gute tekiniki ya immunite colloidal zahabu itanga ibisubizo nyabyo?

Tekinike ikoresha ibice bimwe bya zahabu ya colloidal (24.8 kugeza 39.1 nm) ihujwe na antibodi zihariye, bigatuma antigen-antibody ihuza neza. Ibi bigabanya ibibi bibi no kwivanga inyuma, kugera ku gipimo cyukuri hafi 99%.

2.Ibikoresho byo kwipimisha birashobora kumenya ubwoko bwose bwa malariya?

Ibikoresho byacu bikubiyemo majorPlasmodiumubwoko:P. falciparum, P. vivax, P. ovale, naP. malariya. Ikizamini cya Malariya Ag Pan hamwe nibikoresho bya combo (urugero, Malariya Ag Pf / Pv / Pan Combo Ikizamini) byateguwe kugirango hamenyekane amoko yose akomeye.

3. Nibihe byihuse ibikoresho bitanga ibisubizo?

Ibisubizo birahari muminota 10-15, hamwe numurongo wikizamini ugaragara muminota 2, bigatuma biba byiza gufata ibyemezo byihuse mumavuriro cyangwa murugo.

4. Ibikoresho bikwiriye gukoreshwa ahantu kure cyangwa mumikoro make?

Yego. Ubuhanga bwa immun colloidal zahabu burakomeye kandi ntibusaba ibikoresho byihariye. Ibikoresho bikora neza mubihe bishyushye hamwe namahugurwa make, bigatuma bikwiranye n'uturere twa kure dufite amikoro make.

5. Niki gituma tri-umurongo / combo ibikoresho byiza kuruta ubwoko bumwe?

Tri-line na combo ibikoresho bituma icyarimwe kimenyekanisha amoko menshi mugupimisha kamwe, bikagabanya gukenera kwipimisha kenshi. Ibi bifite agaciro cyane cyane mukarere kanduye malariya ivanze (urugero, uturere dufite byombiP. falciparumnaP. vivax).

Umwanzuro

Ubuhanga bwa immun colloidal zahabu bwahinduye gusuzuma malariya, butanga umuvuduko, ubunyangamugayo, kandi butandukanye. Ibicuruzwa byacu, bigamije kurinda hakiri kare, gukoresha urugo, no gusuzuma byinshi, biha imbaraga abantu, abakozi bashinzwe ubuzima, na gahunda z’ubuzima rusange kugira ngo bamenye malariya bidatinze - ni ngombwa mu kugabanya kwandura no guteza imbere intego zo kurandura malariya ku isi.