Testsealabs Myoglobin/CK-MB/Troponin ⅠCombo Test
Tlhaloso e Khutšoanyane:
 Liphetho tse Potlakileng: Lab-Nepahetse ka Metsotso | Lab-Grade Precision: E ka tšeptjoa ebile e ka tšeptjoa |
| Teko Hohle: Ha ho Ketelo ea Lab e Hlokehang | Boleng bo tiisitsoeng: 13485, CE, Mdsap Compliant |
| E bonolo ebile e tsamaisitsoe: Ho bonolo ho e Sebelisa, Ha ho Mathata | Boikemisetso ba ho Fetisisa: Etsa Teko Ha U le Lapeng |
Myoglobin (MYO)
Myoglobin (MYO) ke heme-protein e atisang ho fumanoa mesifa ea skeletal le ea pelo, e nang le boima ba molek'hule ea 17.8 kDa. E etsa hoo e ka bang 2% ea protheine ea mesifa eohle 'me e ikarabella ho tsamaisa oksijene ka har'a lisele tsa mesifa.
Ha lisele tsa mesifa li senyehile, myoglobin e lokolloa ka potlako maling ka lebaka la boholo ba eona bo fokolang. Ka mor'a lefu la lisele tse amanang le myocardial infarction (MI), myoglobin ke e 'ngoe ea matšoao a pele a nyolohang ka holimo ho maemo a tloaelehileng:
- E eketseha ka mokhoa o lekanyelitsoeng ka holimo ho tekanyo ea pele nakong ea lihora tse 2-4 ka mor'a infarct.
- Litlhōrō ka lihora tse 9-12.
- E khutlela boemong ba pele nakong ea lihora tse 24-36.
Litlaleho tse 'maloa li fana ka maikutlo a lithuso tsa ho lekanya myoglobin ho netefatsa ho ba sieo ha myocardial infarction, ka litekanyetso tse mpe tsa ho bolela esale pele tse fihlang ho 100% tse tlalehiloeng ka linako tse itseng ka mor'a hore matšoao a qale.
Creatine Kinase MB (CK-MB)
Creatine kinase MB (CK-MB) ke enzyme e teng mesifa ea pelo, e nang le boima ba molek'hule ea 87.0 kDa. Creatine kinase ke molek'hule ea dimeric e entsoeng ka lihlopha tse peli ("M" le "B"), tse kopanang ho etsa li-isoenzyme tse tharo: CK-MM, CK-BB, le CK-MB. CK-MB ke isoenzyme e amehang haholo metabolism ea mesifa ea pelo.
Ka mor'a MI, ho lokolloa ha CK-MB maling ho ka bonoa nakong ea lihora tse 3-8 ka mor'a hore matšoao a qale:
- E fihla sehlohlolong nakong ea lihora tse 9-30.
- E khutlela boemong ba pele nakong ea lihora tse 48-72.
CK-MB ke e 'ngoe ea matšoao a bohlokoa ka ho fetisisa a pelo 'me e tsejoa hohle e le letšoao la setso bakeng sa ho hlahloba MI.
Cardiac Troponin I (cTnI)
Cardiac troponin I (cTnI) ke protheine e fumanoang mesifa ea pelo, e nang le boima ba molek'hule ea 22.5 kDa. Ke karolo ea li-subunit complex tse tharo (hammoho le troponin T le troponin C); hammoho le tropomyosin, motsoako ona o laola ts'ebetso ea ATPase e utloang khalsiamo ea actomyosin ka har'a mesifa ea masapo le ea pelo.
Ka mor'a kotsi ea pelo, troponin I e lokolloa maling lihora tse 4-6 ka mor'a hore bohloko bo qale. Mokhoa oa eona oa ho lokolloa o tšoana le CK-MB, empa ha CK-MB e khutlela ho tloaelehileng ka hare ho lihora tsa 72, troponin I e lula e phahame ka matsatsi a 6-10-e fana ka fensetere e telele ea ho lemoha bakeng sa kotsi ea pelo.
cTnI e na le ts'ebetso e phahameng ea ts'enyo ea myocardial, e bonts'itsoeng maemong a kang nako ea perioperative, ho matha ka mor'a marathone, le ho sithabela ha sefuba ho se nang letho. E boetse e lokolloa maemong a pelo ntle le acute myocardial infarction (AMI), joalo ka angina e sa tsitsang, congestive heart failure, le tšenyo ea ischemic ho tsoa ho opereishene ea "coronary artery bypass". Ka lebaka la ho khetheha ha eona le kutloelo-bohloko bakeng sa lisele tsa myocardial, troponin I hona joale ke eona biomarker e ratoang ka ho fetisisa bakeng sa MI.
Myoglobin/CK-MB/Troponin Ⅰ Combo Test
The Myoglobin/CK-MB/Troponin Ⅰ Combo Test ke teko e bonolo e sebelisang motsoako oa li-antibody-coated particles tsa MYO/CK-MB/cTnI le ho tšoara li-reagents ho lemoha MYO, CK-MB, le cTnI maling kaofela, serum kapa plasma ka mokhoa o ikhethileng.
