Li-reagents tse ncha tsa ho lemoha IVD li fetola Tlhahlobo ea Arbovirus

Kokoana-hloko ea Zika, e leng setho sa lelapa la Flaviviridae, e fetisetsoa ho batho haholo-holo ka ho longoa ke monoang oa Aedes o tšoaelitsoeng, o kang Aedes aegypti le Aedes albopictus. Kokoana-hloko ena e ile ea tsejoa ka lekhetlo la pele ka 1947 Merung ea Zika ea Uganda, moo e neng e arotsoe ho tšoene ea rhesus. Ka lilemo tse mashome, tšoaetso ea kokoana-hloko ea Zika e ne e batla e sa tloaeleha 'me e lekanyelitsoe feela maemong a nakoana Afrika le Asia, 'me mafu a mangata a baka matšoao a bobebe kapa a se nang letho. Leha ho le joalo, ka 2015, ho ile ha qhoma seoa se seholo Brazil, se ileng sa namela ka potlako linaheng tse ling tsa Latin America, Caribbean, le ho feta, se hohela tlhokomelo ea lefatše lohle.

Matšoao a tšoaetso ea kokoana-hloko ea Zika hangata a bobebe 'me a ka kenyelletsa feberu, lekhopho, bohloko ba manonyeletso, bohloko ba mesifa, hlooho e bohloko le conjunctivitis. Matšoao ana hangata a hlaha matsatsi a 2 ho isa ho a 7 ka mor'a ho longoa ke monoang o tšoaelitsoeng 'me a nka matsatsi a 2 ho isa ho a 7. Le hoja batho ba bangata ba hlaphoheloa ka ho feletseng ntle le mathata a tebileng, kokoana-hloko ea Zika e 'nile ea amahanngoa le mafu a tebileng a methapo ea kelello, haholo-holo microcephaly ho masea a tsoetsoeng ke bo-'mè ba tšoaelitsoeng nakong ea bokhachane, le lefu la Guillain-Barré ho batho ba baholo.

Ka lebaka la tšokelo e sa khaotseng e hlahisoang ke li-arboviruses tse kang Zika, Chikungunya le Dengue,Testsealabse hlahisitse li-suite tsa li-Advanced in vitro diagnostic reagents (IVD), tse tšoaeang leqhubu la bohlokoa la tlhahlobo e nepahetseng le e potlakileng ea mafu ana. Li-reagents tsena, ho kenyeletsoa Teko ea Zika Virus Antibody IgG/IgM, ZIKA IgG/IgM/Chikungunya IgG/IgM Combo Test, le Dengue NS1/Dengue IgG/IgM/Zika Virus IgG/IgM Combo Test, hammoho le Dengue Dengue NS1/ZigM IgG/IgM e felletseng. Teko ea IgG/IgM/Chikungunya, e etselitsoe ho fetola sebopeho sa tlhahlobo ea arbovirus.

Phephetso e kholo ea ho sebetsana le li-arbovirus tsena ke hore matšoao a bona a pele a tšoana haholo, hangata a lebisa tlhokomelong e fosahetseng. Tafole e latelang e totobatsa matšoao a tloaelehileng a Zika, Dengue le Chikungunya, hammoho le lintlha tsa bohlokoa tsa bongaka, tse bontšang hore na ke hobane'ng ha pherekano e hlaha:

*Ho ipapisitsoe le phuputso ea 2024 ea linyeoe tsa bongaka tse 1,200 libakeng tsa tropike

**Ho kenyeletsoa pokello ea mehlala, lipalangoang, le liteko tsa tatellano

Ka lebaka la ho tšoana hona ho makatsang ha matšoao a pele le litekanyetso tse phahameng tsa tlhahlobo e fosahetseng (e fetang 50% bakeng sa livaerase tse tharo kaofela), ho thata haholo ho bafani ba tlhokomelo ea bophelo ho khetholla lipakeng tsa mafu ana ho ipapisitsoe le tlhahiso ea bongaka feela. Nako e telele e hlokahalang bakeng sa ho netefatsoa ka liteko tse le 'ngoe e ntse e lieha ho phekola le ho laola ho qhoma. Mona ke moo liteko tsa rona tse ncha tsa combo li kenang teng. Ho theha motheong oa liteko tsa karete e le 'ngoe, re thehile li-reagents tsa ho lemoha likarete tse ngata tse ka khethollang mafu a mangata tekong e le' ngoe, ho fokotsa nako ea ho hlahloba ka ho fihla ho 70% le ho fokotsa litekanyetso tsa tlhahlobo e fosahetseng ho ea ka tlase ho 5% litekong tsa meriana.

Zika Virus Antibody IgG/IgM Test: Ho lemoha tšoaetso ea Zika ka Precision

Tlhahlobo ea Zika Virus Antibody IgG/IgM ke tlhahlobo e potlakileng ea chromatographic immunoassay e etselitsoeng ho lemoha boleng ba li-antibodies tsa IgG le IgM ho kokoana-hloko ea Zika maling a motho, serum kapa plasma. Teko ena e sebetsa e le thuso ea bohlokoa tlhahlobong ea tšoaetso ea kokoana-hloko ea Zika. Ka ho bona boteng ba li-antibodies tsena, bafani ba tlhokomelo ea bophelo ba ka tseba hore na mokuli o sa tsoa tšoaetsoa (IgM positive) kapa o kile a ba le ts'oaetso ea nakong e fetileng (IgG positive).

Melemo ea Sehlahisoa: Teko e hlahella ka kutlo ea eona e phahameng haholo (98.6% litekong tsa bongaka), e khona ho lemoha li-antibodies le methating ea pele ea ts'oaetso ha maemo a sesole sa 'mele a le tlase. Sebopeho sa eona se ikhethang (99.2%) se fokotsa ts'ebetso ea ho kopana le li-antibodies tse tsoang ho li-flavivirus tse amanang, ho netefatsa liphello tse tšepahalang. Ho feta moo, lisebelisoa tsa teko li etselitsoe ho tsitsisa nako e telele, ka nako ea nako ea likhoeli tse 24 ha li bolokiloe ho 2-8 ° C, ho fokotsa litšila le ho netefatsa hore ho na le libaka tse ka thōko tse nang le lisebelisoa tse fokolang tsa ketane ea serame.

ZIKA IgG/IgM/Chikungunya IgG/IgM Combo Test: Dual Diagnosis for Related Arboviruses

Tlhahlobo ea ZIKA IgG/IgM/Chikungunya IgG/IgM Combo ke sesebelisoa sa phetoho se lumellang ho lemoha le ho khetholla ka nako e le ’ngoe li-antibodies tsa immunoglobulin M (IgM) le immunoglobulin G (IgG) ho kokoana-hloko ea Zika le kokoana-hloko ea Chikungunya. Chikungunya, joalo ka Zika, ke lefu le jereng menoang le ka bakang bohloko bo tebileng ba manonyeletso, feberu le lekhopho.

Melemo ea Sehlahisoa: Tlhahlobo ena ea combo e felisa tlhokahalo ea tlhahlobo e arohaneng bakeng sa Zika le Chikungunya, ho fokotsa nako ea teko ka 50% ha e bapisoa le liteko tsa motho ka mong (ho tloha ka karolelano ea lihora tse 52 ho isa ho metsotso ea 20). E sebelisa mokhoa o ikhethileng oa ho lemoha likanale tse peli tse netefatsang phapang e hlakileng lipakeng tsa livaerase tsena tse peli, ka sekhahla sa ts'ebetso e ka tlase ho 1%, ho qoba pherekano e ka hlahang matšoao a tšoanang a kliniki. Teko e boetse e hloka sampole e nyane (5µL feela), e etsa hore e be bonolo ho bakuli, haholo bana le batho ba baholo.

Dengue NS1/Dengue IgG/IgM/Zika Virus IgG/IgM Combo Test: Mokhoa o Akaretsang oa Tlhahlobo ea Arbovirus

Dengue NS1/Dengue IgG/IgM/Zika Virus IgG/IgM Combo Test ke tharollo e felletseng e sa lemoheng feela boteng ba kokoana-hloko ea Dengue ka ho lemoha li-antigen tsa NS1, IgG, le IgM empa hape e hlahloba likokoana-hloko tsa Zika IgG le IgM. Dengue ke bothata bo boholo ba bophelo bo botle ba sechaba libakeng tse ngata tsa tropike le tsa tropike, e baka matšoao a fapaneng ho tloha ho bokuli bo bobebe ho isa ho feberu e matla ea dengue hemorrhagic fever e ka behang bophelo kotsing.

Melemo ea Sehlahisoa: Ho kenyelletsoa ha NS1 ho lemoha ha antigen ho thusa ho lemoha Dengue kapele matsatsing a 1-2 ka mor'a ho qala ha matšoao, ka kutloisiso ea 97.3% bakeng sa ho lemoha NS1, e leng ea bohlokoa bakeng sa phekolo e nakong ho thibela mathata a matla (a hlahang ho 10-20% ea linyeoe tse sa phekoloang). Teko ea tlhahlobo ea li-parameter tse ngata (NS1, IgG, IgM bakeng sa Dengue le IgG, IgM bakeng sa Zika) e fana ka boemo bo felletseng ba tlhahlobo, ho thusa bafani ba tlhokomelo ea bophelo ho utloisisa boemo ba ts'oaetso le ho etsa liqeto tse nepahetseng tsa kalafo. Ho feta moo, tlhahlobo e netefalitsoe hore e sebelisoe maemong a fapaneng a kliniki, e bonts'a ts'ebetso e ts'oanang ho lilaboratori tse fapaneng tse nang le coefficient of variation (CV) e ka tlase ho 5%.

Dengue NS1/Dengue IgG/IgM/Zika Virus IgG/IgM/Chikungunya Test: The Ultimate Arbovirus Diagnostic Tool

Teko ea Dengue NS1/Dengue IgG/IgM/Zika Virus IgG/IgM/Chikungunya e nka tlhahlobo ea arbovirus ho isa boemong bo latelang ka ho kopanya bokhoni ba ho lemoha liteko tsohle tse fetileng le ho eketsa tlhahlobo ea li-antibodies tsa Chikungunya IgG le IgM. Teko ena ea bohle-in-one e etselitsoe ho fana ka tlhahlobo e felletseng le e nepahetseng ea mafu a mangata a arbovirus tekong e le 'ngoe.

Melemo ea Sehlahisoa: Tlhahlobo ena e kenyeletsang bohle e fana ka katleho e ke keng ea lekanngoa ka ho lemoha li-arbovirus tse tharo tse kholo ka nako e le 'ngoe, ho fokotsa litšenyehelo tse felletseng ka mokuli ka 40% ha ho bapisoa le liteko tsa motho ka mong le ho fokotsa haholo mosebetsi oa basebetsi ba laboratori. E na le theknoloji e tsoetseng pele ea ho hōlisa matšoao e ntlafatsang maikutlo a ho lemoha bakeng sa lipakane tsohle (karolelano ea kutloisiso ea 98.1% ho bahlahlobisisi bohle), ho netefatsa hore esita le tšoaetso ea boemo bo tlaase ha e fosoe. Teko e boetse e tla le sebopeho se bonolo sa basebelisi le litataiso tse hlakileng tsa tlhaloso ea sephetho, e etsang hore ho be bonolo ho e sebelisa esita le ho basebeletsi ba tsa bophelo bo botle ba nang le boiphihlelo bo fokolang, ka nako ea koetliso ea lihora tse 2 feela tse hlokahalang bakeng sa boiphihlelo.

Likarolo le Melemo eaTestsealabs Li-reagents tsa ho lemoha IVD

• Liphetho tse potlakileng: Liteko tsena kaofela li fana ka sephetho ka nako e khuts'oane, hangata ka mor'a metsotso e 15, e lumellang ho etsoa liqeto kapele mabapi le tlhahlobo le kalafo ea bakuli.
• Kutloelo-bohloko e Phahameng le ho Khetheha: Liteko li etselitsoe ho ba le kutloelo-bohloko haholo (≥97%), ho netefatsa hore ho fumanoa esita le maemo a tlaase a li-antibodies kapa li-antigen, le tse tobileng (≥99%), ho fokotsa kotsi ea ho ba le maikutlo a fosahetseng. Sena se bohlokoa bakeng sa tlhahlobo e nepahetseng le taolo e nepahetseng ea bakuli.
• Mefuta ea Mehlala e Fetohang: Li ka sebelisoa ka mefuta e fapaneng ea sampuli, ho kenyelletsa le menoana ea mali, mali a venous, serum le plasma, e leng se etsang hore li tšoanelehe ho sebelisoa maemong a fapaneng a bongaka le a tlhokomelo.
• Bonolo ba Tšebeliso: Liteko li bonolo ho etsoa 'me li hloka koetliso e fokolang, e leng se etsang hore li fumanehe ho bafani ba tlhokomelo ea bophelo libakeng tse nang le lisebelisoa tse ngata le tse nang le lisebelisoa tse fokolang.
• Liphello tsa sepheo: Liteko tse ngata, tse kang tse sebelisang thekenoloji ea DPP (Dual Path Platform) e nang le patented, li fana ka liphello tsa sepheo ka ho sebelisa sebali se bonolo sa digital se tšoaroang ka letsoho, ho fokotsa monyetla oa phoso ea motho ka tlhaloso ea sephetho.

Qetello

Testsealabsmefuta e mecha ea li-reagents tsa ho lemoha IVD bakeng sa likokoana-hloko tsa Zika, Chikungunya, le Dengue e emela tsoelo-pele e kholo lefapheng la tlhahlobo ea arbovirus. Ka lebaka la ho tšoana ho hoholo ha matšoao a pele le litekanyetso tse nyarosang tsa tlhahlobo e fosahetseng (tse fetang 50%) har'a mafu ana, liteko tsa rona tsa combo, tse entsoeng ho tsoa litekong tsa karete e le 'ngoe, tse ka lemohang mafu a mangata ka nako e le ngoe ka litekanyetso tsa tlhahlobo e fosahetseng tse ka tlase ho 5% le linako tsa tlhahlobo tse ka tlase ho metsotso e 20, li bohlokoa haholo. Ka melemo ea bona e ikhethang ea sehlahisoa ho kenyelletsa kutlo e phahameng, boits'oaro, ts'ebetso, le boiketlo ba tšebeliso, li-reagents tsena li behiloe ho hlalosa bocha hore na mafu a arbovirus a fumanoa joang le ho laoloa. Ka ho fa bafani ba tlhokomelo ea bophelo lisebelisoa tse nepahetseng, tse potlakileng, le tse feletseng tsa ho hlahloba, li-reagents tsena li na le monyetla oa ho ntlafatsa liphello tsa mokuli, ho ntlafatsa tlhokomelo ea mafu, le ho kenya letsoho ho laola ho phatloha ha arbovirus ka katleho. Ha moroalo oa lefats'e oa mafu a arbovirus a ntse a eketseha, liteko tsena tse ncha li reretsoe ho bapala karolo ea bohlokoa ntoeng khahlanong le litšokelo tsena tsa bohlokoa tsa bophelo bo botle ba sechaba.