Malaria: Kakaretso le Lisebelisoa tsa Teko tse Potlakileng tse Tsoang Pele Li tsamaisoa ke Immune Colloidal Gold Technique

Malaria ke eng?

Malaria ke lefu le behang bophelo kotsing le bakoang kePlasmodiumlikokoana-hloko, tse fetisetsoang ho batho ka ho longoa ke basali ba nang le tšoaetsoAnophelesmenoang. Likokoana-hloko li latela potoloho e rarahaneng ea bophelo: ha li kena 'meleng, li qala ka ho hlasela lisele tsa sebete hore li ikatise, ebe li lokolla li-sporozoite tse tšoaetsang lisele tse khubelu tsa mali. Ka har’a lisele tse khubelu tsa mali, likokoana-hloko li ikatisa ka potlako; ha lisele li phatloha, li ntša chefo maling, e leng se bakang matšoao a matla a kang ho tsieleha ka tšohanyetso, feberu e matla (hangata e fihlang ho 40°C), mokhathala, ’me maemong a matla, ho hlōleha ha litho tsa ’mele kapa lefu.

Bana ba ka tlase ho lilemo tse 5, bakhachane, le batho ba nang le boits'ireletso ba mmele bo fokolang ba kotsing e kholo. Leha litlhare tse thibelang malaria joalo ka chloroquine li ntse li le bohlokoa bakeng sa kalafo, tlhahlobo ea pele le e nepahetseng ke senotlolo sa taolo e sebetsang le ho thibela phetiso. Mehato ea ho laola menoang (mohlala, matlooa a ho robala, meriana e bolaeang likokoanyana) le eona e phetha karolo ea bohlokoa thibelong, empa ho fumanoa ka nako e ntse e le motheo oa taolo ea malaria.

Theknoloji ea Khauta ea Immune Colloidal: Phetoho ea liteko tse potlakileng tsa Malaria

Lisebelisoa tsa tlhahlobo tse potlakileng tsa Malaria, ho kenyeletsoa leMalaria Ag Pf/Pv Tri-line Test Cassette, Malaria Ag Pf/Pan Test, Malaria Ag Pf/Pv/Pan Combo Test,Malaria Ag Pv Test Cassette, leMalaria Ag Pf Test Cassette, hona joale sebelisa mokhoa oa ho itšireletsa mafung oa colloidal khauta bakeng sa ho nepahala ho ntlafetseng. Theknoloji ena e hlahile e le mokhoa o ka sehloohong oa lisebelisoa tsa tlhahlobo tse potlakileng tsa malaria, o sebelisa likaroloana tsa khauta tsa colloidal tse kopantsoeng le li-antibodies ho bona li-antigen tsa malaria maling a felletseng.

Kamoo E Sebetsang Kateng

Mokhoa oa khauta oa 'mele oa colloidal o sebetsa ho latela molao-motheo oa tšebelisano ea antigen-antibody:

• Likaroloana tsa khauta ea Colloidal (ka boholo ba junifomo ho tloha ho 24.8 ho isa ho 39.1 nm) li tlameletsoe ho masole a 'mele a shebaneng le li-antigen tse amanang le malaria (mohlala, histidine-rich protein II bakeng saP. falciparum).
• Ha sampole ea mali e sebelisoa k'haseteng ea teko, li-antibody tsena tsa khauta li tlamella li-antigen leha e le life tse teng tsa malaria tse teng, 'me li etsa mela e mebala-bala mothating oa teko.

Melemo ea Bohlokoa

• Lebelo: E fana ka sephetho ka mor'a metsotso e 10–15, 'me mela e qalang e hlaha ka mor'a metsotso e 2.
• Ho nepahala: E fihlella ho nepahala ha ho sibolloa hoo e batlang e le 99%, ho fokotsa mefokolo ea bohata.
• Ho lemoha mefuta e mengata: E khetholla li-antigen ho tsoa ho tse kholoPlasmodiummefuta, ho kenyeletsaP. falciparum, P. vivax, P. ovale, leP. malariae.
• Robustness: Ts'ebetso e tsitsitseng ho pholletsa le lihlopha le mefuta ea lisampole, e nang le tšitiso e fokolang ea bokamorao, esita le maemong a haelloang ke lisebelisoa.

Sehlahisoa sa rona sa Portfolio: E etselitsoe maemo a fapaneng

Re fana ka mefuta e mengata ea lisebelisoa tsa tlhahlobo tse potlakileng tsa malaria tse ipapisitseng le mokhoa oa khauta oa immune colloidal, o etselitsoeng ho fihlela litlhoko tsa ts'ireletso ea pele, tlhahlobo ea lapeng le tlhahlobo e kholo. Tafole e ka tlase e akaretsa likarolo tsa bona tsa bohlokoa:

Netefatso ea Clinical ea Tri-line Kits

Phuputso e entsoeng naheng ea Tanzania e ile ea lekola katleho ea bongaka ea lisebelisoa tsa mela e meraro ka mokhoa oa ho itšireletsa mafung oa colloidal gold:

Likopo ho Maemo ho Fetisisa

• Tšireletso ea pele: Li-Kits tse kang Malaria Ag Pv Test Cassette li thusa batho ba libakeng tse kotsing e kholo ho lemoha tšoaetso hang-hang, ho thibela ho fetela ho lefu le matla.
• Teko ea lapeng: Meralo e bonolo ea mosebedisi (mohlala, Cassette ea Malaria Ag Pf) e lumella malapa ho itlhahloba ntle le koetliso e khethehileng, ho netefatsa ho kenella ka nako.
• Tlhahlobo e kholo: Liteko tsa Combo le Pan-species (mohlala, Malaria Ag Pf/Pv/Pan Combo Test) li nolofatsa tlhahlobo ea batho ba bangata likolong, libakeng tsa mosebetsi, kapa nakong ea likoluoa ​​​​tse tšehetsang thibelo e potlakileng.

LBH

1. Mokhoa oa 'mele oa ho itšireletsa mafung oa colloidal gold o netefatsa liphello tse nepahetseng joang?

Mokhoa ona o sebelisa likaroloana tsa khauta tsa colloidal tse boholo bo lekanang (24.8 ho isa ho 39.1 nm) tse kopantsoeng le li-antibodies tse khethehileng, ho netefatsa hore ho tlamahane ha antigen-antibody. Sena se fokotsa mefokolo ea bohata le tšitiso ea morao, ho fihlela sekhahla sa ho nepahala se haufi le 99%.

2. Na lisebelisoa tsee tsa tlhahlobo li ka lemoha mefuta eohle ea likokoana-hloko tsa malaria?

Li-kits tsa rona li koahela tse kholoPlasmodiummefuta:P. falciparum, P. vivax, P. ovale, leP. malariae. Tlhahlobo ea Malaria Ag Pan le lisebelisoa tsa ho kopanya (mohlala, Malaria Ag Pf/Pv/Pan Combo Test) li etselitsoe ho lemoha mefuta eohle e meholo.

3. Lisebelisoa li fana ka sephetho kapele hakae?

Liphetho li fumaneha nakong ea metsotso e 10-15, 'me mela ea liteko hangata e hlaha nakong ea metsotso e 2, e leng se etsang hore e be tse loketseng ho etsa liqeto ka potlako maemong a tleliniki kapa lapeng.

4. Na lisebelisoa li loketse ho sebelisoa libakeng tse hole kapa tse nang le mehloli e fokolang?

Ee. Mokhoa oa khauta oa 'mele oa colloidal o matla ebile ha o hloke lisebelisoa tse khethehileng. Li-Kits li sebetsa ka mokhoa o ts'epahalang maemong a leholimo a chesang le ka koetliso e fokolang, e etsang hore li tšoanelehe libakeng tse hole tse nang le lisebelisoa tse fokolang.

5. Ke eng e etsang hore li-tri-line/combo kits li be betere ho feta lisebelisoa tsa mofuta o le mong?

Li-tri-line le li-combo kits li lumella ho fumanoa ha mefuta e mengata ka nako e le 'ngoe tekong e le' ngoe, ho fokotsa tlhoko ea tlhahlobo e pheta-phetoang. Sena se bohlokoa haholo libakeng tse nang le tšoaetso ea malaria e tsoakiloeng (mohlala, libaka tse nang le bobeli ba tsonaP. falciparumleP. vivax).

Qetello

Mokhoa oa 'mele oa ho itšireletsa mafung o fetotse tlhahlobo ea malaria, o fana ka lebelo, ho nepahala le ho feto-fetoha ha maemo. Sehlahisoa sa rona, se etselitsoeng ts'ireletso ea pele, ts'ebeliso ea lapeng, le tlhahlobo e kholo, se matlafatsa batho ka bomong, basebeletsi ba tsa bophelo bo botle, le mananeo a bophelo bo botle ba sechaba ho lemoha lefu la mala hang-hang - e leng ea bohlokoa bakeng sa ho fokotsa phetiso le ho ntšetsa pele lipheo tsa ho felisa malaria lefatšeng ka bophara.