Testsealabs COT Cotinine Test
Incazelo emfushane:
I-COT Cotinine Test (Umchamo) iyi-lateral flow chromatographic immunoassay yokutholwa kwekhwalithi ye-cotinine emchameni.
 Imiphumela Esheshayo: Ilebhu Inembe Ngamaminithi | Ukunemba Kwebanga Lebhu: Okunokwethenjelwa & Okuthembekile |
| Hlola Noma Kukuphi: Akukho Ukuvakashelwa Kwelebhu Okudingekile | Ikhwalithi Eqinisekisiwe: 13485, CE, I-Mdsap Iyahambisana |
| Ilula futhi Yasakazwa: Kulula ukuyisebenzisa, I-Zero Hassle | I-Ultimate Convenience: Hlola Ngokunethezeka Ekhaya |
I-Cotinine iyi-metabolite yesigaba sokuqala se-nicotine, i-alkaloid enobuthi ekhiqiza ukugqugquzelwa kwe-autonomic ganglia kanye nesimiso sezinzwa esimaphakathi kubantu.
I-Nicotine iyisidakamizwa lapho cishe wonke amalungu omphakathi obhema ugwayi achayeka kuso, noma ngokuthintana ngqo noma ngokuhogela okwesibili. Ngaphezu kukagwayi, i-nicotine iphinde itholakale nokudayiswa njengesithako esisebenzayo ekwelapheni esikhundleni sokubhema njenge-nicotine gum, ama-transdermal patches, nezifutho zamakhala.
Kusampula yomchamo wamahora angama-24, cishe u-5% wedosi ye-nicotine ukhishwa njengesidakamizwa esingashintshiwe, ngo-10% njenge-cotinine kanye nama-35% njenge-hydroxyl cotinine; ukugxila kwamanye ama-metabolites kukholakala ukuthi angaphansi kuka-5%.
Nakuba i-cotinine kucatshangwa ukuthi iyi-metabolite engasebenzi, iphrofayili yayo yokuqeda izinze kakhulu kune-nicotine, encike kakhulu kumchamo we-pH. Ngenxa yalokho, i-cotinine ibhekwa njengophawu oluhle lwebhayoloji lokunquma ukusetshenziswa kwe-nicotine.
I-plasma half-life ye-nicotine icishe ibe yimizuzu engama-60 ngemva kokuhogela umoya noma ngokuphathwa kwabazali. I-Nicotine ne-cotinine ziqedwa ngokushesha yizinso; iwindi lokutholwa kwe-cotinine emchameni ezingeni elinqunyiwe lika-200 ng/mL kulindeleke ukuthi libe yizinsuku ezi-2-3 ngemva kokusetshenziswa kwe-nicotine.
I-COT Cotinine Test (Urine) iveza umphumela omuhle lapho i-cotinine emchameni idlula u-200 ng/mL.
