I-Testsealabs Pioneers Impilo Yabesifazane Ngemikhiqizo Yokuxilonga Ethuthukile

Esimeni esithuthukayo sempilo yabesifazane, i-Testsealabs ihamba phambili njengomsunguli ozinikele, ozibophezele ekuthuthukiseni izixazululo ezisezingeni eliphezulu ezibeka phambili inhlalakahle yabesifazane. Ngokuqonda okujulile kwezinselelo abesifazane ababhekana nazo ekugcineni impilo enhle yesitho sangasese sowesifazane sangasese, inkampani yethule imikhiqizo emibili yokuxilonga: i-Candida Albicans/Trichomonas Vaginalis/Gardnerella Vaginalis Antigen Combo Test Cassette kanye ne-Vaginitis Multitest Kit (I-Enzymatic assay). Le mikhiqizo ayigcini nje ngokugcizelela ukugxila okungantengantengi kwe-Testsealabs empilweni yabesifazane kodwa futhi imelela ukuhambela phambili okubalulekile ekuxilongeni okunembayo nangempumelelo kwezimo ezivamile zesitho sangasese sowesifazane.

Ukusabalala Kwezifo Ezithweni Zangasese: Ukukhathazeka Kwezempilo Emhlabeni Wonke

Izifo ezithweni zangasese yindaba esabalele ethinta izigidi zabesifazane emhlabeni jikelele. Ngokwe-World Health Organization (WHO), cishe u-40% wabesifazane emhlabeni wonke bazophathwa izifo zesitho sangasese esikhathini esithile ekuphileni kwabo, kanti lesi sibalo sikhuphukela ku-70% kwabesifazane abashadile. Lezi zifo, okuhlanganisa nalezo ezibangelwa i-Candida albicans, i-Trichomonas vaginalis, ne-Gardnerella vaginalis, zingabangela uchungechunge lwezimpawu kusukela ekuphathekeni kabi kuya ezinkingeni ezinzima zempilo. Zingaholela ekuvuvukeni kwe-pelvic, ukubeletha ngaphambi kwesikhathi, kanye nengozi eyengeziwe yezinye izifo ezithathelwana ngocansi, okugqamisa isidingo esiphuthumayo samathuluzi okuxilonga asebenzayo.

Indaba Eyisibonelo 1: Umzabalazo Ka-Emily Nokutheleleka Okuphindaphindiwe

U-Emily, uchwepheshe oneminyaka engama-30 ubudala, ubelokhu ebhekene nezifo eziphindaphindayo zesitho sangasese sowesifazane isikhathi esingaphezu konyaka. Waba nokulunywa okungapheli, ukukhishwa okungavamile, nokungakhululeki ngesikhathi socansi. Izindlela zendabuko zokuxilonga, ezifana (i-white - discharge microscopy), ngokuvamile zihluleka ukunikeza ukuxilongwa okucacile, okuholela ekwelapheni okungasebenzi. Izinga lakhe lempilo lathinteka kakhulu, lathinta kokubili umsebenzi wakhe nobudlelwano bomuntu siqu. Kwaze kwaba yilapho ehlolwa nge-Candida Albicans/Trichomonas Vaginalis/Gardnerella Vaginalis Antigen Combo Test Cassette lapho ethola khona ukuhlonzwa okunembile kwe-co - infection ye-Candida albicans ne-Gardnerella vaginalis. Ngokwelashwa okuhlosiwe okusekelwe emiphumeleni yokuhlolwa, u-Emily ekugcineni wathola ukukhululeka, futhi izimpawu zakhe zadamba phakathi namasonto ambalwa.

Imikhiqizo Yokuxilonga Entsha ye-Testsealabs

Candida Albicans/Trichomonas Vaginalis/Gardnerella Vaginalis Antigen Combo Test Cassette

Leli khasethi lokuhlola elingu-3 – in – 1 liklanyelwe ukuthola ama-antigen amagciwane amathathu avamile esithweni sangasese ngasikhathi sinye. Isebenzisa ubuchwepheshe be-immunochromatographic assay, inikeza imiphumela esheshayo nenembile phakathi kwemizuzu eyi-15 - 20. Ikhasethi lokuhlola liyasebenziseka - lisebenziseka kalula, okulenza lifanelekele ukusetshenziswa ezindaweni ezihlukahlukene zokunakekelwa kwempilo, kusukela ezibhedlela ezinkulu kuye emitholampilo emincane. Kungumdlalo - uguquko ekuxilongweni kwezifo ezithweni zangasese, njengoba kuvumela abahlinzeki bezempilo ukuthi babone ngokushesha izinto eziyimbangela futhi baqale ukwelashwa okufanele, okunciphisa isikhathi iziguli ezisichitha zihlushwa izimpawu.

I-Vaginitis Multitest Kit (i-Enzymatic assay)

I-7 – in – 1 Vaginitis Multitest Kit imele intuthuko enkulu ekuxilongweni kwempilo yesitho sangasese sowesifazane. Isetshenziselwa ukutholwa kwe-in – vitro qualitative of biomarkers eziningi ekusithekeni kwesitho sangasese sowesifazane, okuhlanganisa i-hydrogen peroxide (H₂O₂), i-sialidase (SNA), i-leukocyte esterase (LE), i-proline aminopeptidase (PIP), N – acetyl – β – D – glucosaminidase (NAG), i-oxida value pH. I-biomarker ngayinye idlala indima ebalulekile ekuhloleni izici ezihlukene zempilo yesitho sangasese sowesifazane:

• I-Hydrogen Peroxide (H₂O₂): Kusetshenziswa ngokomtholampilo ukuze kutholwe ukuthi ingabe ibhalansi ye-ecological yangasese iphazamisekile. I-H₂O₂, ngaphansi kwesenzo se-peroxidase, ihlangana ne-substrate ye-tetramethylbenzidine (TMB) ukukhiqiza umkhiqizo onemibala, i-tetramethylbenzidine ene-oxidized, ebonakala i-turquoise noma eluhlaza okwesibhakabhaka - eluhlaza. Ukujula kombala kuhambisana ngokuqondile nokugxiliswa kwe-H₂O₂.
• I-Sialidase (SNA): Isetshenziselwa ukuxilonga i-bacterial vaginosis. I-SNA i-hydrolyze i-substrate ethize ye-sodium neuraminidase, futhi umkhiqizo owumphumela, i-bromoindolyl, isabela ngonjiniyela wombala i-nitroblue tetrazolium chloride ukuze ibe mpunga – okwesibhakabhaka noma impunga – eluhlaza, nokujula kombala okubonisa umsebenzi we-SNA.
• I-Leukocyte Esterase (LE): Isiza ekuxilongeni i-bacterial vaginitis. I-LE i-hydrolyze i-substrate ethize i-pyrrolidyl - naphthylamide, futhi i-naphthol ekhishiwe - 4 - sulfonic acid isabela ukuze yakhe inhlanganisela ye-quinone, ebonakala ebomvana noma ensomi - ebomvana, nokuqina kombala ngokulingana nomsebenzi we-LE.
• I-Proline Aminopeptidase (PIP): Isetshenziselwa futhi ukuhlonza i-bacterial vaginosis. I-PIP i-hydrolyze i-substrate ethize ye-proline p - i-nitroaniline, iveza umbala ophuzi, futhi ukujula kombala kuhlobene nomsebenzi we-PIP.
• N – acetyl – β – D – glucosaminidase (NAG): Kusetshenziswa ngokomtholampilo ukuxilonga i-trichomoniasis kanye ne-candidiasis. I-NAG i-hydrolyze i-substrate ethile ethi N – acetyl – β – D – glucosaminide, ikhipha i-p – nitrophenol, ebonakala insomi – ebomvana noma ebomvana, futhi ukujula kombala kubonisa umsebenzi we-NAG.
• I-Oxidase (OA): Isetshenziselwa ukuxilonga i-vaginitis engacacisiwe. I-OA i-oxidize i-substrate ye-tetramethyl – p – phenylenediamine ibe inhlanganisela ye-quinone, ebonakala eluhlaza okwesibhakabhaka, futhi ukujula kombala kuhambisana nomsebenzi we-OA.
• Inani le-pH: Isiza ukuhlukanisa phakathi kwe-trichomoniasis kanye ne-candidiasis. Ibhulokhi ye-pH ephepheni lokuhlola iqukethe i-substrate kanjiniyela yombala i-cresol eluhlaza, eshintsha umbala kububanzi be-pH obungu-3.6 – 5.4. Lapho i-pH ishintsha isuka ku-4.1 iye ku-5.1, umbala uyashintsha usuka kophuzi uye kophuzi ngokukhanyayo, uluhlaza okwesibhakabhaka ngokukhanyayo – ophuzi, oluhlaza sasibhakabhaka, noluhlaza okwesibhakabhaka – oluhlaza.

Ukubaluleka Komtholampilo Nezinzuzo

I-Vaginitis Multitest Kit inikeza ukuhlolwa okuphelele kwempilo yesitho sangasese sowesifazane, okwenza abahlinzeki bezempilo bakwazi ukuxilonga ngokunembile izinhlobo ezahlukene ze-vaginitis, okuhlanganisa i-bacterial vaginosis (BV), i-trichomoniasis, i-candidiasis, kanye ne-nonspecific vaginitis, kanye nokuhlola indawo ezungezile ye-microecological yangasese. Ngokunikeza ulwazi oluningiliziwe mayelana nama-biomarker amaningi, kuyasiza ekwenzeni izinhlelo zokwelashwa ezenzelwe umuntu siqu, ukuthuthukisa ukusebenza kahle kokwelashwa, kanye nokunciphisa izinga lokuphinda kwezifo zesitho sangasese sowesifazane.

Isifundo 2: Uhambo Luka-Sarah lokuya ekululameni

USarah, owesifazane oneminyaka engu-28 ubudala okhulelwe, wayephatheke kabi futhi ephuma nokukhishwa okungavamile esithweni sangasese. Ekhathazekile ngomthelela ongaba khona ekukhulelweni kwakhe, wahlolwa nge-Vaginitis Multitest Kit. Ukuhlolwa kwembula ukungalingani ku-microecology yakhe yesitho sangasese sowesifazane, namazinga aphakeme e-sialidase kanye ne-pH engavamile, okubonisa i-bacterial vaginosis. Umhlinzeki wakhe wokunakekelwa kwezempilo ukwazile ukumnikeza ngokushesha ukwelashwa okufanele, okungagcini nje ngokudambisa izimpawu zakhe kodwa futhi kwanciphisa ingozi yokusikwa ngaphambi kwesikhathi, nokuqinisekisa umphumela wokukhulelwa onempilo.

Ukuqhathanisa Nezindlela Zokuxilonga Zendabuko

Izindlela zendabuko zokuxilonga i-vaginitis, njengokuthi (i-white - discharge microscopy), isiko lebhaktheriya lokuphuma kwesitho sangasese sowesifazane, ukuhlolwa kokuzwela kwezidakamizwa, kanye ne-electronic colposcopy, kunemikhawulo eminingana. I-Microscopy inokuzwela okuguquguqukayo futhi ingase igeje ezinye izifo, kuyilapho isiko lebhaktheriya lidla isikhathi - kuthatha izinsuku ezimbalwa ukuthola imiphumela. Ukuhlolwa kokuzwela kwezidakamizwa kanye ne-colposcopy ye-elekthronikhi nakho kuyabiza futhi kudinga amathuluzi akhethekile nabasebenzi abaqeqeshiwe. Ngokuphambene, imikhiqizo yokuxilonga ye-Testsealabs inikeza imiphumela esheshayo, ukunemba okuphezulu, kanye nezindleko - ukusebenza kahle, okuyenza ifinyeleleke kalula ukuze isetshenziswe kabanzi.

Isiphetho

Sengiphetha, i-Candida Albicans/Trichomonas Vaginalis ka-Testsealabs/Gardnerella Vaginalis Antigen Combo Test Cassette kanye ne-Vaginitis Multitest Kit imelela isinyathelo esibalulekile esiya phambili ekuxilongeni izifo zesitho sangasese sowesifazane. Le mikhiqizo inikeza izixazululo ezinembile, ezisheshayo, neziphelele, ezibhekana nemikhawulo yezindlela zokuxilonga zendabuko. Ngokubeka eqhulwini impilo yabesifazane kanye nokutshala izinto ezintsha, i-Testsealabs yenza umthelela omuhle ezimpilweni zabesifazane emhlabeni wonke, iqinisekisa ukuthi bayafinyelela kumathuluzi okuxilonga angcono kakhulu okugcina impilo enhle yesitho sangasese sowesifazane. Njengoba inkampani iqhubeka nokukhula futhi ithuthuka, isazibophezele emkhankasweni wayo wokuthuthukisa impilo yabesifazane ngobuchwepheshe obusezingeni eliphezulu nokunakekelwa kozwelo.