Ikizamini COT Cotinine Ikizamini
Ibisobanuro bigufi:
Ikizamini cya COT Cotinine (Urine) ni immunoassay itembera ya chromatografique kugirango tumenye neza cotinine mu nkari.
 Ibisubizo Byihuse: Laboratoire-Nukuri muminota | Laboratoire-Icyiciro Cyuzuye: Yizewe & Yizewe |
| Ikizamini Ahantu hose: Nta laboratoire isabwa | Ubwiza bwemewe: 13485, CE, Mdsap Yubahiriza |
| Byoroheje & Byoroheje: Byoroshye-Gukoresha, Zeru Hassle | Amahirwe meza: Gerageza neza murugo |
Cotinine ni metabolite yo mu cyiciro cya mbere cya nikotine, alkaloide y'ubumara itanga imbaraga zo gutera imbaraga za ganglia autonomic na sisitemu yo hagati yo hagati mu bantu.
Nikotine ni ibiyobyabwenge abantu bose bagize umuryango unywa itabi bagaragariza, haba muburyo butaziguye cyangwa guhumeka. Usibye itabi, nikotine iraboneka no mubucuruzi nkibintu byingenzi bigira uruhare mu kuvura itabi nka nicotine gum, ibibyimba bya transdermal, hamwe nizuru.
Mu cyitegererezo cy’amasaha 24, hafi 5% yumuti wa nikotine usohoka nkumuti udahindutse, 10% nka cotinine na 35% nka hydroxyl cotinine; kwibumbira hamwe kwa metabolite byizera ko bitarenze 5%.
Mugihe cotinine ikekwa kuba metabolite idakora, umwirondoro wacyo wo kurandura urahagaze neza kuruta icya nikotine, ahanini kikaba giterwa ninkari pH. Nkigisubizo, cotinine ifatwa nkikimenyetso cyiza cyibinyabuzima cyo kumenya nikotine.
Plasma igice cyubuzima bwa nikotine ni iminota 60 ikurikira guhumeka cyangwa ubuyobozi bwababyeyi. Nikotine na cotinine birandurwa vuba nimpyiko; idirishya ryo gutahura cotinine mu nkari kurwego rwo guca 200 ng / mL biteganijwe ko hazaba iminsi 2-33 nyuma yo gukoresha nikotine.
Ikizamini cya COT Cotinine (Inkari) gitanga umusaruro ushimishije mugihe cotinine mu nkari irenze 200 ng / mL.
