Ikizamini cya OXY Oxycodone Ikizamini
Ibisobanuro bigufi:
 Ibisubizo Byihuse: Laboratoire-Nukuri muminota | Laboratoire-Icyiciro Cyuzuye: Yizewe & Yizewe |
| Ikizamini Ahantu hose: Nta laboratoire isabwa | Ubwiza bwemewe: 13485, CE, Mdsap Yubahiriza |
| Byoroheje & Byoroheje: Byoroshye-Gukoresha, Zeru Hassle | Amahirwe meza: Gerageza neza murugo |
Oxycodone: Amakuru y'ingenzi
Oxycodone ni igice cya sintetike ya opioide ifite imiterere isa na codeine. Yakozwe muguhindura thebaine, alkaloide iboneka muri popium.
Kimwe na opiate agoniste, oxycodone itanga ububabare bukora kuri reseptor ya opioid mu ruti rw'umugongo, ubwonko, ndetse bikaba bishoboka no mubice byanduye. Byateganijwe kugabanya ububabare buringaniye kandi bukabije munsi yizina ryubucuruzi rizwi, harimo:
OxyContin®
Tylox®
Percodan®
Percocet®
Ikigaragara ni uko Tylox®, Percodan®, na Percocet® zirimo urugero ruto rwa oxycodone hydrochloride ihujwe n’ibindi bisobanuro (urugero, acetaminofeni cyangwa aspirine), mu gihe OxyContin® igizwe gusa na hydrocloride ya oxycodone mu buryo bwo gusohora igihe.
Oxycodone metabolize ikoresheje demethylation muri oxymorphone na noroxycodone. Ku gipimo kimwe cya 5mg yo mu kanwa, 33-61% isohoka mu nkari z'amasaha 24, hamwe n'ibigize ibice:
Ibiyobyabwenge bidahindutse (13–19%)
Ibiyobyabwenge byanduye (7-29%)
Oxymorphone ya conjugated (13-14%)
Idirishya ryo kumenya oxycodone mu nkari byitezwe ko risa n'iry'izindi opioide (urugero, morphine).
Ikizamini cya OXY Oxycodone gitanga umusaruro mwiza mugihe urugero rwa oxycodone yinkari zirenga 100 ng / mL. Kugeza ubu, Ubuyobozi bushinzwe serivisi zita ku buzima bwo mu mutwe (SAMHSA) ntabwo bwashyizeho uburyo bwo gusuzuma bwagabanijwe bwa oxycodone nziza.
