Ikizamini TnI Intambwe imwe Troponin estGupima
Ibisobanuro bigufi:
 Ibisubizo Byihuse: Laboratoire-Nukuri muminota | Laboratoire-Icyiciro Cyuzuye: Yizewe & Yizewe |
| Ikizamini Ahantu hose: Nta laboratoire isabwa | Ubwiza bwemewe: 13485, CE, Mdsap Yubahiriza |
| Byoroheje & Byoroheje: Byoroshye-Gukoresha, Zeru Hassle | Amahirwe meza: Gerageza neza murugo |
Cardiac Troponin I (cTnI)
Cardiac troponin I (cTnI) ni poroteyine iboneka mu mitsi yumutima ifite uburemere bwa 22.5 kDa. Nibice bigize subunit eshatu zigizwe na troponine T na troponine C. Hamwe na tropomyosine, uru ruganda rwubatswe rugize igice cyingenzi kigenga ibikorwa bya calcium-yumutima wa ATPase ya actomyosine mumitsi ya skeletale na cardiac.
Nyuma yo gukomeretsa k'umutima, troponine I irekurwa mumaraso nyuma yamasaha 4-6 nyuma yububabare butangiye. Uburyo bwo kurekura cTnI busa na CK-MB, ariko mugihe urwego rwa CK-MB rusubira mubisanzwe nyuma yamasaha 72, troponine I ikomeza kuzamuka muminsi 6-10, bityo igatanga idirishya rirerire ryo kumenya ibikomere byumutima.
Umwihariko wo gupima cTnI kugirango umenye ibyangiritse bya myocardial byagaragaye mubihe nkigihe cya perioperative, nyuma ya marato yiruka, hamwe nihungabana ryigituza. Cardiac troponin I narekuye nayo yanditse mubihe byumutima uretse infarction ikaze ya myocardial (AMI), harimo angina idahindagurika, kunanirwa k'umutima, hamwe no kwangirika kwa ischemic bitewe no kubaga imitsi ya aroni.
Kubera umwihariko wacyo hamwe nubukangurambaga mumyanya myocardial, troponine Mperutse kuba biomarker ikunzwe cyane infarction myocardial.
TnI Intambwe imwe Troponin I Igerageza
Ikizamini cya TnI Intambwe imwe ya Troponine I ni ikizamini cyoroshye gikoresha uruvangitirane rwa cTnI ya antibody yatewe hamwe no gufata reagent kugirango uhitemo neza cTnI mumaraso yose / serumu / plasma. Urwego ntarengwa rwo kumenya ni 0.5 ng / mL.
