Testsealabs TnI Imwe Nhanho Troponin ⅠMuedzo
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Cardiac Troponin I (cTnI)
Cardiac troponin I (cTnI) ipuroteni inowanikwa mumhasuru yemwoyo ine huremu hwe 22.5 kDa. Icho chikamu chetatu-subunit complex inosanganisira troponin T uye troponin C. Pamwe chete ne tropomyosin, iyi yakaoma yehutano inoumba chikamu chikuru chinogadzirisa calcium-sensitive ATPase basa re actomyosin mu striated skeletal uye cardiac muscle.
Mushure mekukuvara kwemwoyo kunoitika, troponin I inosunungurwa muropa maawa 4-6 mushure mekutanga kwemarwadzo. Nzira yekusunungurwa yecTnI yakafanana neCK-MB, asi nepo CK-MB mazinga achidzokera kune zvakajairika mushure memaawa 72, troponin I inoramba yakasimudzwa kwemazuva 6-10, nokudaro ichipa hwindo refu rekuonekwa kwekukuvara kwemwoyo.
Iyo yakanyanya kujeka yezviyero zvecTnI zvekuzivikanwa kwekukuvara kwemyocardial kwakaratidzwa mumamiriro ezvinhu akadai senguva yeperioperative, mushure mekumhanya kwemarathon, uye blunt chest trauma. Cardiac troponin I kusunungurwa kwakanyorwawo mumamiriro emwoyo kunze kweacute myocardial infarction (AMI), kusanganisira angina isina kugadzikana, congestive heart failure, uye ischemic kukuvara nekuda kwekuvhiyiwa kwecoronary artery bypass.
Nekuda kwehukuru hwayo hwepamusoro uye kunzwisiswa mumyocardial tishu, troponin I ichangobva kuve iyo inonyanya kufarirwa biomarker yemyocardial infarction.
TnI Imwe Nhanho Troponin I Test
Iyo TnI Imwe Nhanho Troponin I Muedzo bvunzo yakapusa inoshandisa musanganiswa wecTnI antibody-yakavharwa zvimedu uye reagent yekutora kuti ione cTnI muropa rose/serum/plasma. Chiyero chechidiki chekuonekwa ndeye 0.5 ng/mL.
