Testsealabs COT Cotinine Test
Lus piav qhia luv luv:
COT Cotinine Test (Urine) yog ib qho lateral flow chromatographic immunoassay rau kev kuaj pom zoo ntawm cotinine hauv cov zis.
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Cotinine yog thawj theem metabolite ntawm nicotine, ib qho tshuaj lom alkaloid uas ua rau stimulation ntawm autonomic ganglia thiab hauv nruab nrab paj hlwb hauv tib neeg.
Nicotine yog ib yam tshuaj uas yuav luag txhua tus tswvcuab hauv zej zog haus luam yeeb raug nthuav tawm, txawm tias los ntawm kev sib cuag ncaj qha lossis nqus tau ob txhais tes. Ntxiv nrog rau kev haus luam yeeb, nicotine kuj tseem muaj nyob rau hauv kev lag luam raws li cov khoom muaj nyob rau hauv kev hloov pauv kev haus luam yeeb xws li nicotine gum, transdermal thaj ua rau thaj, thiab tshuaj tsuag qhov ntswg.
Hauv cov zis 24-teev, kwv yees li 5% ntawm cov tshuaj nicotine raug tshem tawm raws li cov tshuaj tsis hloov pauv, nrog 10% ua cotinine thiab 35% raws li hydroxyl cotinine; ntseeg tau tias qhov concentrations ntawm lwm cov metabolites yog suav tias yog tsawg dua 5%.
Thaum cotinine xav tias yog ib qho tsis muaj zog metabolite, nws qhov kev tshem tawm qhov profile yog qhov ruaj khov dua li cov nicotine, uas feem ntau cov zis pH nyob ntawm. Yog li ntawd, cotinine yog suav hais tias yog ib qho khoom siv roj ntsha zoo rau kev txiav txim siab siv nicotine.
Lub plasma ib nrab-lub neej ntawm nicotine yog kwv yees li 60 feeb tom qab nqus pa los yog parenteral tswj. Nicotine thiab cotinine raug tshem tawm sai sai los ntawm lub raum; Lub qhov rais ntawm kev kuaj pom cov cotinine hauv cov zis ntawm qhov txiav tawm ntawm 200 ng / mL yuav tsum muaj txog li 2-3 hnub tom qab siv nicotine.
COT Cotinine Test (Urine) tau txais txiaj ntsig zoo thaum cov cotinine hauv cov zis ntau dua 200 ng / mL.
