Malungo: Mwachidule ndi Zida Zapamwamba Zoyesera Zofulumira Mothandizidwa ndi Immune Colloidal Gold Technique

Kodi malungo ndi chiyani?

Malungo ndi matenda owopsa omwe amayamba chifukwa chaPlasmodiummajeremusi, opatsirana kwa anthu kudzera kulumidwa ndi kachilombo mkaziAnophelesudzudzu. Tizilombo toyambitsa matenda timatsatira moyo wovuta kwambiri: tikalowa m'thupi, amayamba kuwononga maselo a chiwindi kuti achuluke, kenako amamasula sporozoites zomwe zimawononga maselo ofiira a magazi. M’maselo ofiira a magazi, tizilomboti timabalana mofulumira; maselo akamaphulika, amatulutsa poizoni m'magazi, zomwe zimayambitsa zizindikiro zoopsa monga kuzizira mwadzidzidzi, kutentha thupi (nthawi zambiri kufika 40 ° C), kutopa, ndipo nthawi zambiri, kulephera kwa chiwalo kapena imfa.

Ana osapitirira zaka 5, amayi apakati, komanso anthu omwe ali ndi chitetezo chofooka cha mthupi ali pachiopsezo chachikulu. Ngakhale mankhwala oletsa malungo monga chloroquine amakhalabe ofunikira kuchiza, kuzindikira koyambirira komanso kolondola ndikofunikira pakuwongolera bwino ndikupewa kufalikira. Njira zopewera udzudzu (monga ma neti, mankhwala ophera tizirombo) nawonso amathandizanso kwambiri popewera udzudzu, koma kuzindikirika kwake munthawi yake kumakhalabe chinsinsi cha kuletsa malungo.

Technique Immune Colloidal Gold Technique: Kusintha Mayeso a Malaria Rapid

Zida zoyezera malungo mwachangu, kuphatikizaMalaria Ag Pf/Pv Tri-line Test Cassette, Mayeso a Malaria Ag Pf/Pan, Malaria Ag Pf/Pv/Pan Combo Test,Malaria Ag Pv Test Cassette,ndiKaseti Yoyesera ya Malaria Ag Pf, tsopano gwiritsani ntchito njira ya chitetezo chamthupi ya colloidal golide kuti ikhale yolondola. Ukadaulowu watulukira ngati njira yotsogola yoyesera zida zoyesera malungo mwachangu, pogwiritsa ntchito tinthu tating'ono tagolide tomwe timalumikizana ndi ma antibodies kuti tizindikire ma antigen a malungo m'magazi athunthu.

Mmene Imagwirira Ntchito

Njira ya chitetezo chamthupi ya colloidal golide imagwira ntchito pamfundo yolumikizana ndi antigen-antibody:

• Tinthu tating'onoting'ono tomwe timakhala tomwe timakhala tomwe timakhala tomwe timafanana ndi 24.8 nm mpaka 39.1 nm) timakhala ndi ma antibodies omwe amalimbana ndi ma antigen enieni a malungo (mwachitsanzo, histidine-rich protein II forP. falciparum).
• Magazi akagwiritsidwa ntchito pa kaseti yoyesera, ma antibody agolide amenewa amamangiriza ku ma antigen aliwonse omwe alipo, kupanga mizere yamitundu yowoneka pamzere woyesera.

Ubwino waukulu

• Liwiro: Amapereka zotsatira mu mphindi 10-15, mizere yoyambira ikuwonekera mkati mwa mphindi ziwiri.
• Kulondola: Imakwaniritsa zolondola za pafupifupi 99%, ndikuchepetsa zoyipa zabodza.
• Kuzindikira zamitundu yambiri: Imazindikiritsa ma antigen kuchokera ku zazikuluPlasmodiummitundu, kuphatikizapoP. falciparum, P. vivax, P. ovale,ndiP. malariae.
• Kulimba: Kuchita mosasinthasintha pamabatchi ndi mitundu ya zitsanzo, zosokoneza pang'ono zakumbuyo, ngakhale pazokonda zochepa.

Zathu Zogulitsa: Zopangidwira Zosiyanasiyana

Timapereka zida zingapo zoyezera malungo mwachangu kutengera luso la chitetezo chamthupi la colloidal golidi, lopangidwa kuti likwaniritse zofunikira pakudziteteza koyambirira, kuyezetsa kunyumba, ndikuwunika kwakukulu. Tebulo ili m'munsiyi likufotokoza mwachidule mbali zazikulu za zinthuzi:

Kutsimikizika Kwachipatala kwa Zida za Mizere Yatatu

Kafukufuku wa ku Tanzania adawunika momwe zida za mizere itatu imathandizira pogwiritsa ntchito njira ya chitetezo chamthupi ya colloidal gold:

Mapulogalamu Pazochitika Zonse

• Chitetezo choyambirira: Zida monga Malaria Ag Pv Test Cassette zimathandiza anthu omwe ali m'madera omwe ali pachiopsezo kuti azindikire matenda adakali aang'ono, zomwe zimathandiza kuti asayambe kudwala.
• Kuyeza kunyumba: Mapangidwe osavuta kugwiritsa ntchito (mwachitsanzo, Malaria Ag Pf Test Cassette) amalola mabanja kudziyesa okha popanda maphunziro apadera, kuwonetsetsa kulowererapo panthawi yake.
• Kuzindikira kwakukulu: Mayeso a Combo ndi mitundu ya pan-species (mwachitsanzo, Mayeso a Malaria Ag Pf/Pv/Pan Combo) amathandizira kuyesa kwa anthu ambiri m'masukulu, kuntchito, kapena panthawi ya miliri, kuthandizira kutetezedwa mwachangu.

FAQ

1. Kodi njira ya chitetezo cha mthupi colloidal gold imatsimikizira bwanji zotsatira zolondola?

Njirayi imagwiritsa ntchito tinthu tating'ono tagolide ta colloidal (24.8 mpaka 39.1 nm) cholumikizidwa ndi ma antibodies enieni, kuwonetsetsa kuti kumangika kwa antigen-antibody. Izi zimachepetsa zolakwika zabodza komanso kusokoneza zakumbuyo, ndikukwaniritsa kulondola kwapafupi ndi 99%.

2. Kodi zida zoyezerazi zitha kuzindikira mitundu yonse ya tizilombo ta malungo?

Zida zathu zimaphimba zazikuluPlasmodiummitundu:P. falciparum, P. vivax, P. ovale,ndiP. malariae. Mayeso a Malaria Ag Pan ndi zida zophatikizira (monga Malaria Ag Pf/Pv/Pan Combo Test) adapangidwa kuti azitha kuzindikira mitundu yonse yayikulu.

3. Kodi zida zimatulutsa zotsatira mwachangu bwanji?

Zotsatira zimapezeka mkati mwa mphindi 10-15, mizere yoyesera nthawi zambiri imawonekera mkati mwa mphindi ziwiri, zomwe zimawapangitsa kukhala abwino popanga zisankho mwachangu m'malo azachipatala kapena kunyumba.

4. Kodi zidazi ndizoyenera kugwiritsidwa ntchito kumadera akutali kapena ocheperako?

Inde. Njira yachitetezo cha chitetezo chamthupi ya colloidal ndi yamphamvu ndipo safuna zida zapadera. Ma Kits amagwira ntchito modalirika kumadera otentha komanso osaphunzitsidwa pang'ono, kuwapangitsa kukhala oyenera kumadera akutali omwe ali ndi zinthu zochepa.

5. Ndi chiyani chomwe chimapangitsa zida za mizere itatu/combo kukhala zabwino kuposa zida zamtundu umodzi?

Mizere itatu ndi ma combo kits amalola kuzindikira mitundu ingapo nthawi imodzi muyeso limodzi, kuchepetsa kufunika koyesa mobwerezabwereza. Izi ndizofunikira makamaka m'madera omwe ali ndi malungo osakanikirana (mwachitsanzo, madera omwe ali ndi onse awiriP. falciparumndiP. vivax).

Mapeto

Njira ya chitetezo chamthupi ya colloidal gold yasintha matenda a malungo, kupereka liwiro, kulondola, ndi kusinthasintha. Zogulitsa zathu, zomwe zimapangidwira kuti zitetezedwe msanga, kugwiritsa ntchito kunyumba, ndi kuyesa kwakukulu, zimalimbikitsa anthu, ogwira ntchito zachipatala, ndi mapulogalamu a zaumoyo kuti azindikire malungo mwamsanga-ofunika kwambiri kuchepetsa kufala kwa malungo ndi kupititsa patsogolo zolinga za kuthetsa malungo padziko lonse.