Testsealabs Myoglobin/CK-MB/Troponin Ⅰ Gwajin Combo
Takaitaccen Bayani:
 Sakamako cikin gaggawa: Lab-Madaidaici a cikin mintuna | Matsakaicin darajar Lab: Abin dogaro & Amintacce |
| Gwaji Ko'ina: Babu Ziyarar Lab da ake buƙata | Ingantattun Ingancin: 13485, CE, Mai yarda da Mdsap |
| Mai Sauƙi & Sauƙi: Sauƙi-da-Amfani, Hassle Sifili | Mafi dacewa: Gwaji da kwanciyar hankali a Gida |
Myoglobin (MYO)
Myoglobin (MYO) shine furotin heme-protein wanda aka saba samu a cikin kwarangwal da tsoka na zuciya, tare da nauyin kwayoyin halitta na 17.8 kDa. Ya ƙunshi kusan 2% na jimlar furotin tsoka kuma yana da alhakin jigilar iskar oxygen a cikin ƙwayoyin tsoka.
Lokacin da ƙwayoyin tsoka suka lalace, ana fitar da myoglobin cikin sauri cikin jini saboda ƙananan girmansa. Bayan mutuwar nama mai alaƙa da ciwon zuciya na zuciya (MI), myoglobin yana ɗaya daga cikin alamomin farko da ya tashi sama da matakan al'ada:
- Yana ƙaruwa a aunawa sama da tushe a cikin sa'o'i 2-4 bayan ciwon ciki.
- Kololuwa a 9-12 hours.
- Ya dawo kan asali a cikin sa'o'i 24-36.
Rahotanni da yawa sun ba da shawarar taimakon ma'aunin myoglobin don tabbatar da rashin ciwon zuciya na zuciya, tare da ƙimar tsinkaya mara kyau har zuwa 100% da aka ruwaito a cikin takamaiman lokuta bayan bayyanar cututtuka.
Creatine Kinase MB (CK-MB)
Creatine kinase MB (CK-MB) wani enzyme ne da ke cikin tsokar zuciya, tare da nauyin kwayoyin halitta na 87.0 kDa. Creatine kinase wani kwayar halitta dimeric ne da aka samu daga sassa biyu ("M" da "B"), wanda ya haɗu ya zama isoenzymes uku: CK-MM, CK-BB, da CK-MB. CK-MB shine isoenzyme da ke da hannu a cikin metabolism na ƙwayar tsoka na zuciya.
Bayan MI, ana iya gano sakin CK-MB cikin jini a cikin awanni 3-8 bayan bayyanar cututtuka:
- Kololuwa a cikin sa'o'i 9-30.
- Ya dawo kan asali a cikin sa'o'i 48-72.
CK-MB yana ɗaya daga cikin mahimman alamomin zuciya kuma an san shi sosai azaman alamar gargajiya don bincikar MI.
Cardiac Troponin I (cTnI)
Cardiac troponin I (cTnI) furotin ne da ake samu a tsokar zuciya, tare da nauyin kwayoyin halitta na 22.5 kDa. Yana daga cikin hadaddun subunit guda uku (tare da troponin T da troponin C); tare da tropomyosin, wannan hadaddun yana daidaita ayyukan ATPase mai raɗaɗi na calcium na actomyosin a cikin skeletal da tsoka na zuciya.
Bayan rauni na zuciya, an saki troponin I a cikin jini 4-6 hours bayan jin zafi. Tsarin sakin sa yayi kama da CK-MB, amma yayin da CK-MB ke dawowa al'ada a cikin sa'o'i 72, troponin I ya kasance yana ɗaukaka har tsawon kwanaki 6-10-yana samar da taga mai tsayi don raunin zuciya.
cTnI yana da ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙayyadaddun bugun zuciya, wanda aka nuna a cikin yanayi kamar lokacin aiki, gudu bayan marathon, da raunin ƙirji. Hakanan ana sake shi a cikin yanayin zuciya ban da myocardial infarction (AMI), kamar angina mara tsayayye, gazawar zuciya, da lalacewar ischemic daga aikin tiyata na jijiyoyin jini. Saboda ƙayyadaddun ƙayyadaddun sa da ƙwarewa ga nama na myocardial, troponin I yanzu shine mafi fifikon biomarker don MI.
Myoglobin/CK-MB/Troponin Ⅰ Gwajin Haɗuwa
Gwajin Combo Myoglobin/CK-MB/Troponin Ⅰ Gwajin Combo ne mai sauki wanda ke amfani da hadewar MYO/CK-MB/cTnI barbashi masu rufaffiyar antibody da kama reagents don tantance MYO, CK-MB, da cTnI a cikin jini gaba daya, jini, ko plasma.
