Testsealabs COT Cotinine Test
Inkcazelo emfutshane:
Uvavanyo lweCOT Cotinine (Umchamo) yi-lateral flow chromatographic immunoassay yokufumanisa umgangatho we-cotinine kumchamo.
 Iziphumo eziKhawulezayo: ILab-Chanekile kwiMizuzu | Ukuchaneka kweBanga leLebhu: ethembekileyo kwaye ethembekileyo |
| Vavanya naphi na: Akukho tyelelo lwaseLab olufunekayo | Umgangatho oqinisekisiweyo: 13485, CE, iMdsap iyahambelana |
| Ilula kwaye iSetyenzisiwe: Kulula ukuyisebenzisa, iZero Hassle | ULulelo olugqibeleleyo: Vavanya ngokukhululeka ekhaya |
I-Cotinine yinqanaba lokuqala le-metabolite ye-nicotine, i-alkaloid enetyhefu eyenza ukuvuselela i-autonomic ganglia kunye ne-central nervous system ebantwini.
Inikotini lichiza apho phantse onke amalungu oluntu olutshayayo abhencwa kulo, nokuba kukudibana ngokuthe ngqo okanye ngokuphefumla ngesandla sesibini. Ukongeza kwicuba, i-nicotine ikwafumaneka ngokurhweba njengesithako esisebenzayo kunyango lokubuyisela ukutshaya njenge-nicotine gum, i-transdermal patches, kunye nezitshizi zempumlo.
Kwisampula yomchamo weeyure ezingama-24, malunga ne-5% yedosi ye-nicotine ikhutshwe njengeyeza elingatshintshiyo, kunye ne-10% njenge-cotinine kunye ne-35% njenge-hydroxyl cotinine; Ugxininiso lwezinye i-metabolites lukholelwa ukuba lungaphantsi kwe-5%.
Nangona i-cotinine icingelwa ukuba i-metabolite engasebenzi, iphrofayili yayo yokuphelisa izinzile ngakumbi kune-nicotine, eyona nto ixhomekeke kumchamo we-pH. Ngenxa yoko, i-cotinine ithathwa njengophawu olulungileyo lwebhayoloji ekumiseleni ukusetyenziswa kwenikotini.
Ubomi be-plasma besiqingatha senikotini bumalunga nemizuzu engama-60 emva kokuphefumla okanye ulawulo lwe-parenteral. I-Nicotine kunye ne-cotinine zipheliswa ngokukhawuleza ngezintso; ifestile yokufumanisa i-cotinine kumchamo kwinqanaba lokunqunyulwa kwe-200 ng / mL kulindeleke ukuba ibe yi-2-3 iintsuku emva kokusetyenziswa kwe-nicotine.
Uvavanyo lwe-COT Cotinine (Umchamo) luvelisa umphumo omuhle xa i-cotinine kumchamo idlula i-200 ng / mL.
