Testsealabs Myoglobin/CK-MB/Troponin ⅠCombo Test
Inkcazelo emfutshane:
 Iziphumo eziKhawulezayo: ILab-Chanekile kwiMizuzu | Ukuchaneka kweBanga leLebhu: ethembekileyo kwaye ethembekileyo |
| Vavanya naphi na: Akukho tyelelo lwaseLab olufunekayo | Umgangatho oqinisekisiweyo: 13485, CE, iMdsap iyahambelana |
| Ilula kwaye iSetyenzisiwe: Kulula ukuyisebenzisa, iZero Hassle | ULulelo olugqibeleleyo: Vavanya ngokukhululeka ekhaya |
IMyoglobin (MYO)
I-Myoglobin (MYO) yi-heme-protein ngokuqhelekileyo ifumaneka kwi-skeletal kunye ne-cardiac muscle, ene-molecular weight 17.8 kDa. Iquka malunga ne-2% yeprotheyini ye-muscle iyonke kwaye inoxanduva lokuthutha i-oksijini ngaphakathi kweeseli ze-muscle.
Xa iiseli zezihlunu zonakalisiwe, i-myoglobin ikhutshwa ngokukhawuleza egazini ngenxa yobukhulu bayo obuncinci. Ukulandela ukufa kwezicubu ezinxulumene ne-myocardial infarction (MI), i-myoglobin yenye yeempawu zokuqala zokunyuka ngaphezu kwamanqanaba aqhelekileyo:
- Inyuka ngokulinganayo ngaphezu kwesiseko phakathi kweeyure ze-2-4 emva kwe-infarct.
- Incopho kwiiyure ze-9-12.
- Ibuyela kwisiseko phakathi kweeyure ezingama-24-36.
Iingxelo ezininzi zibonisa uncedo lokulinganisa i-myoglobin ekuqinisekiseni ukungabikho kwe-myocardial infarction, kunye namaxabiso aqikelelweyo abi ukuya kuthi ga kwi-100% echazwe ngexesha elithile emva kokuqalisa kweempawu.
Creatine Kinase MB (CK-MB)
I-Creatine kinase MB (CK-MB) yi-enzyme ekhoyo kwi-cardiac muscle, ene-molecular weight 87.0 kDa. I-Creatine kinase yi-molecule ye-dimeric eyenziwe kwiinqununu ezimbini ("M" kunye ne "B"), ezidibanisa ukwenza i-isoenzymes ezintathu: CK-MM, CK-BB, kunye ne-CK-MB. I-CK-MB yi-isoenzyme ebandakanyeka kakhulu kwi-metabolism yezicubu ze-cardiac muscle.
Ukulandela i-MI, ukukhutshwa kwe-CK-MB egazini kunokubonwa kwiiyure ze-3-8 emva kokuqala kweempawu:
- Incopho phakathi kwe 9-30 iiyure.
- Ibuyela kwisiseko phakathi kweeyure ezingama-48-72.
I-CK-MB yenye yezona zinto zibalulekileyo zophawu lwentliziyo kwaye yamkelwa ngokubanzi njengophawu lwemveli lokuxilonga i-MI.
I-Cardiac Troponin I (cTnI)
I-Cardiac troponin I (cTnI) yiprotheni efumaneka kwi-cardiac muscle, ene-molecular weight 22.5 kDa. Iyingxenye ye-subunit complex complex (kunye ne-troponin T kunye ne-troponin C); kunye ne-tropomyosin, le ngxaki ilawula umsebenzi we-ATPase we-calcium-sensitive we-actomyosin kwi-striated skeletal and cardiac muscle.
Emva kokulimala kwentliziyo, i-troponin I ikhutshwa egazini kwiiyure ezingama-4-6 emva kokuqala kweentlungu. Ipateni yokukhululwa kwayo ifana ne-CK-MB, kodwa ngelixa i-CK-MB ibuyela ngokuqhelekileyo kwiiyure ze-72, i-troponin I ihlala iphakanyisiwe kwiintsuku ze-6-10-ukubonelela ngefestile yokufumanisa ixesha elide lokulimala kwenhliziyo.
I-cTnI inomlinganiselo ophezulu womonakalo we-myocardial, obonakaliswe kwiimeko ezifana nexesha le-perioperative, i-post-marathon ibaleka, kunye nokwenzakala kwesifuba esibuhlungu. Ikwakhutshwa nakwiimeko zentliziyo ngaphandle kwe-acute myocardial infarction (AMI), efana ne-angina engazinzanga, ukungaphumeleli kwentliziyo, kunye nomonakalo we-ischemic ovela kwi-coronary artery bypass operation. Ngenxa yokuchaneka kwayo okuphezulu kunye novakalelo lwezicubu ze-myocardial, i-troponin I ngoku yeyona nto ikhethwayo kwi-biomarker ye-MI.
Myoglobin/CK-MB/Troponin Ⅰ Combo Test
I-Myoglobin/CK-MB/Troponin Ⅰ Combo Test luvavanyo olulula olusebenzisa indibaniselwano ye-MYO/CK-MB/cTnI ye-antibody-coated particles kunye nokubamba i-reagents ukukhetha ngokukhethiweyo i-MYO, CK-MB, kunye ne-cTnI kwigazi elipheleleyo, i-serum, okanye i-plasma.
