Isifo seengcongconi: Isishwankathelo kunye neeKits zoVavanyo oluKhawulezayo oluPhakamileyo oluXhaswa yi-Immune Colloidal Gold Technique

Yintoni iMalaria?

Imalariya sisifo esisongela ubomi esibangelwa sisifoiPlasmodiumizifunxi-gazi, ezisasazwa ebantwini ngokulunywa yimazi eyosulelekileyoAnophelesiingcongconi. Ezi zifunxi-gazi zilandela umjikelo wobomi ontsonkothileyo: xa zingena emzimbeni, ziqala zihlasele iiseli zesibindi ukuze ziphindaphindeke, emva koko zikhuphe ii-sporozoites ezosulela iiseli ezibomvu zegazi. Kwiiseli ezibomvu zegazi, ezi zifunxi-gazi zizala ngokukhawuleza; xa iiseli ziqhekeza, zikhupha i-toxins egazini, ezibangela iimpawu ezinzima ezifana nokuqhaqhazela ngokukhawuleza, umkhuhlane ophezulu (ngokuqhelekileyo ufikelela kuma-40 ° C), ukukhathala, kwaye kwiimeko ezinzima, ukungaphumeleli kwamalungu okanye ukufa.

Abantwana abangaphantsi kweminyaka emi-5 ubudala, abasetyhini abakhulelweyo, kunye nabantu abanamajoni omzimba abuthathaka ngabona basemngciphekweni omkhulu. Ngelixa amachiza okulwa nesifo seengcongconi njenge chloroquine ehlala ebaluleke kakhulu kunyango, ukuxilongwa kwangoko nangokuchanekileyo ngundoqo kulawulo olusebenzayo kunye nokuthintela usulelo. Amanyathelo okulawula iingcongconi (umzekelo, iinethi zokulala, amayeza okubulala izinambuzane) nawo adlala indima ebalulekileyo ekuthinteleni, kodwa ukufunyanwa kwangethuba kusesisiseko solawulo lwemalariya.

I-Immune Colloidal Gold Technique: Ukutshintsha uVavanyo oluKhawulezayo lweMalariya

Izixhobo zovavanyo olukhawulezileyo lweMalariya, kuqukaI-Malaria Ag Pf/Pv Ikhasethi yoVavanyo lomgca wesithathu, Malaria Ag Pf/Pan Test, Malaria Ag Pf/Pv/Pan Combo Test,Malaria Ag Pv Test Cassette, kwayeIkhasethi yoVavanyo lweMalaria Ag Pf, ngoku sebenzisa ubuchule begolide bomzimba we-colloidal ukuchaneka okuphuculweyo. Le teknoloji iye yavela njengeyona ndlela iphambili kwiikiti zovavanyo olukhawulezayo lwemalariya, kusetyenziswa amasuntswana egolide e-colloidal adityaniswe nezilwa-buhlungu zokubona iiantigens zemalariya egazini lilonke.

Ingaba isebenza kanjani

Indlela yegolide ye-immune colloidal isebenza kumgaqo wokusebenzisana kwe-antigen-antibody:

• Amasuntswana egolide e-Colloidal (anobukhulu obufanayo obususela kwi-24.8 ukuya kwi-39.1 nm) abotshelelwa kwizilwa-buhlungu ezijolise kwii-antigens zesifo seengcongconi (umz., i-histidine-rich protein II yeP. falciparum).
• Xa isampulu yegazi isetyenziswa kwikhasethi yovavanyo, ezi zixhobo zegolide-antibody zibophelela kuzo naziphi na iiantigens zemalariya ezikhoyo, zenze imigca enemibala ebonakalayo kumcu wovavanyo.

Izinto Eziluncedo Ezingundoqo

• Isantya: Inika iziphumo kwi-10-15 imizuzu, kunye nemigca yokuqala evela kwimizuzu emi-2.
• Ukuchaneka: Ukufumana ukuchaneka kokuchongwa phantse kwe-99%, kuncitshiswe izinto ezingalunganga.
• Ukufunyanwa kweentlobo ezininzi: Ichonga ii-antigens kwezinkuluiPlasmodiumiintlobo, kuqukaP. falciparum, P. vivax, P. ovale, kwayeP. malariae.
• Ukomelela: Ukusebenza okuhambelanayo kuzo zonke iibhetshi kunye neentlobo zeesampulu, kunye nokuphazamiseka okuncinci okungasemva, nakwisetingi ezisikelwe umda.

IPotfoliyo yethu yeMveliso: Yenzelwe iimeko ezahlukeneyo

Sinikezela ngoluhlu lweekiti zovavanyo olukhawulezayo lwemalariya esekwe kubuchule begolide bomzimba we-colloidal, eyilelwe ukuhlangabezana neemfuno zokhuseleko lwangethuba, uvavanyo lwasekhaya, kunye novavanyo olukhulu. Le theyibhile ingezantsi ishwankathela iimpawu zabo eziphambili:

Ukuqinisekiswa koNyango lweeKhithi zomgca wesithathu

Uphononongo lwasendle eTanzania luvavanye ukusebenza kweklinikhi kweekhithi zemigca emithathu kusetyenziswa ubuchule begolide bomzimba we-colloidal:

Usetyenziso Kwimiba Ephela

• Ukukhuselwa kwangethuba: Iikhithi ezifana neMalaria Ag Pv Test Cassette yenza ukuba abantu abakwiindawo ezisemngciphekweni omkhulu baqaphele usulelo kwangethuba, nto leyo ethintela ukuqhubela phambili kwisifo esiqatha.
• Uvavanyo lwasekhaya: Uyilo olusebenziseka lula (umzekelo, i-Malaria Ag Pf Test Cassette) ivumela iintsapho ukuba zizivavanye ngaphandle koqeqesho olukhethekileyo, ziqinisekisa ungenelelo ngexesha elifanelekileyo.
• Ukuhlolwa okukhulu: Iimvavanyo ze-Combo kunye ne-pan-species (umzekelo, i-Malaria Ag Pf/Pv/Pan Combo Test) iphucula uvavanyo lobunzima ezikolweni, kwiindawo zokusebenza, okanye ngexesha lokuqhambuka, ukuxhasa ukunyanzeliswa ngokukhawuleza.

FAQ

1. Ubuchule begolide be-immune colloidal buqinisekisa njani iziphumo ezichanekileyo?

Ubuchule busebenzisa amasuntswana egolide e-colloidal ngokobungakanani obulinganayo (24.8 ukuya kwi-39.1 nm) edityaniswe nezilwa-buhlungu ezithile, iqinisekisa ukubophelela okungaguqukiyo kwe-antigen-antibody. Oku kunciphisa ama-negative obuxoki kunye nokuphazamiseka kwemvelaphi, ukufezekisa izinga lokuchaneka kufutshane ne-99%.

2. Ingaba ezi zixhobo zovavanyo zinokuzibona zonke iintlobo zezifunxi-gazi zemalariya?

Iikhithi zethu zibandakanya ezinkuluiPlasmodiumiintlobo:P. falciparum, P. vivax, P. ovale, kwayeP. malariae. Uvavanyo lwe-Malaria Ag Pan kunye nezixhobo ze-combo (umzekelo, i-Malaria Ag Pf/Pv/Pan Combo Test) ziyilelwe ukufunyaniswa ngokubanzi kwazo zonke iindidi eziphambili.

3. Zikhawuleza kangakanani iikhithi ukuzisa iziphumo?

Iziphumo zifumaneka ngaphakathi kwemizuzu eyi-10-15, kunye nemigca yovavanyo ehlala ibonakala ngaphakathi kwemizuzu emi-2, iyenza ibe yinto efanelekileyo yokwenza izigqibo ngokukhawuleza kwiisetingi zeklinikhi okanye zasekhaya.

4. Ngaba iikhithi zikulungele ukusetyenziswa kwiindawo ezikude okanye ezinobutyebi obuphantsi?

Ewe. Indlela yegolide ye-immune colloidal yomelele kwaye ayifuni zixhobo zikhethekileyo. Iikiti zisebenza ngokuthembekileyo kwimozulu eshushu kunye noqeqesho oluncinci, okwenza ukuba zilungele imimandla ekude enezixhobo ezinqongopheleyo.

5. Yintoni eyenza iikhithi ze-tri-line/combo zibengcono kuneekhithi ze-single-species?

Iikiti ze-Tri-line kunye ne-combo zivumela ukufunyanwa kwangaxeshanye iintlobo ezininzi kuvavanyo olunye, ukunciphisa imfuno yokuvavanya ngokuphindaphindiweyo. Oku kubaluleke kakhulu kwimimandla enosulelo lwemalariya exutyiweyo (umzekelo, iindawo ezinazo zombiniP. falciparumkwayeP. vivax).

Ukuqukumbela

Indlela yegolide ye-immune colloidal iguqule ukuxilonga isifo seengcongconi, ibonelela ngesantya, ukuchaneka, kunye nokuguquguquka. Ipotfoliyo yethu yemveliso, eyenzelwe ukukhuselwa kwangethuba, ukusetyenziswa kwekhaya, kunye nokuhlolwa okukhulu, kuxhobisa abantu, abasebenzi bezempilo, kunye neenkqubo zempilo yoluntu ukuba zibone isifo seengcongconi ngokukhawuleza-ezibalulekileyo ekunciphiseni usulelo kunye nokuqhubela phambili iinjongo zokuphelisa isifo seengcongconi.