I-Testsealabs Pioneers yeMpilo yabasetyhini abaneeMveliso eziPhambili zokuHlola

Kwimeko ehlala iguquka yempilo yabasetyhini, i-Testsealabs imi phambili njengomqambi ozinikeleyo, ozibophelele ekuphuhliseni izisombululo ezibukhali ezibeka phambili intlalontle yabasetyhini. Ngokuqonda okunzulu kwimingeni abafazi abajongene nayo ekugcineni impilo efanelekileyo ye-vaginal, inkampani iye yazisa iimveliso ezimbini zokuxilonga i-revolutionary: i-Candida Albicans / Trichomonas Vaginalis / Gardnerella Vaginalis Antigen Combo Test Cassette kunye ne-Vaginitis Multitest Kit (I-Enzymatic assay). Ezi mveliso azigxininisi kuphela ugqaliselo olungagungqiyo lwe-Testsealabs kwimpilo yabasetyhini kodwa zikwamela umtsi obalulekileyo oya phambili kuxilongo oluchanekileyo nolusebenzayo lweemeko eziqhelekileyo zelungu lobufazi.

Ukuxhaphaka kwezifo ze-Vaginal: Inkxalabo yeMpilo yeHlabathi

Usulelo kwilungu lobufazi ngumba oxhaphakileyo ochaphazela izigidi zabasetyhini kwihlabathi liphela. Ngokutsho koMbutho wezeMpilo weHlabathi (i-WHO), malunga ne-40% yabasetyhini kwihlabathi jikelele bayakufumana usulelo lwelungu lobufazi ngaxa lithile ebomini babo, kwaye eli nani linyuke liye kutsho kuma-70% kwabasetyhini abatshatileyo. Olu sulelo, kuqukwa nolo lubangelwa yiCandida albicans, iTrichomonas vaginalis, kunye neGardnerella vaginalis, lunokubangela uluhlu lweempawu ukusuka ekungakhululeki kancinci ukuya kwiingxaki ezinzima zempilo. Bangakhokelela kwisifo sokuvuvukala kwe-pelvic, umsebenzi wangaphambi kwexesha, kunye nomngcipheko okhulayo wezinye izifo ezithathelwana ngesondo, zigxininisa imfuno engxamisekileyo yezixhobo zokuxilonga ezisebenzayo.

I-Case Study 1: Umzabalazo kaEmily kunye noSulelo oluRecurrent

U-Emily, oneminyaka engama-30 ubudala-ubudala obuchwephesha, ebejongene nosulelo lwelungu lobufazi oluqhubekayo ngaphezulu konyaka. Wayesoloko erhawuzelelwa, ephuma umchamo ngendlela engaqhelekanga, kwaye engonwabanga ngexesha lokwabelana ngesondo. Izindlela zokuxilonga eziqhelekileyo, ezifana (ezimhlophe - i-microscopy yokukhupha), kaninzi ayiphumelelanga ukubonelela ngokuxilongwa okucacileyo, okukhokelela kunyango olungasebenziyo. Umgangatho wobomi bakhe wachaphazeleka kakhulu, uchaphazela umsebenzi wakhe kunye nobudlelwane bomntu. Kwakungekho de wavavanywa ngeCandida Albicans kaTestsealabs/Trichomonas Vaginalis/Gardnerella Vaginalis Antigen Combo Test Cassette apho wafumana uxilongo oluchanekileyo losulelo oluhlangeneyo lweCandida albicans kunye neGardnerella vaginalis. Ngonyango olujoliswe kuyo olusekelwe kwiziphumo zovavanyo, ekugqibeleni uEmily wafumana isiqabu, kwaye iimpawu zakhe zehla kwiiveki ezimbalwa.

Testsealabs 'Innovative Diagnostic Products

Candida Albicans/Trichomonas Vaginalis/Gardnerella Vaginalis Antigen Combo Test Cassette

Le 3 - in - 1 ikhasethi yovavanyo yenzelwe ukukhangela ii-antigens ze-pathogens ezintathu eziqhelekileyo ze-vaginal ngaxeshanye. Ukusebenzisa iteknoloji yokuvavanya i-immunochromatographic, inika iziphumo ezikhawulezayo nezichanekileyo ngaphakathi kwe-15 - 20 imizuzu. Ikhasethi yovavanyo iyasebenziseka - inobubele, iyenza ilungele ukusetyenziswa kwiindawo ezahlukeneyo zokhathalelo lwempilo, ukusuka kwizibhedlele ezinkulu ukuya kwiikliniki ezincinci. Kungumdlalo - utshintsho ekuxilongweni kosulelo lobufazi, njengoko luvumela ababoneleli bezempilo ukuba bachonge ngokukhawuleza ii-causative agents kwaye baqalise unyango olufanelekileyo, ukunciphisa ixesha izigulane ezichitha ukubandezeleka kwiimpawu.

I-Vaginitis Multitest Kit (i-Enzymatic assay)

I-7-in - 1 Vaginitis Multitest Kit imele ukuqhubela phambili okubonakalayo ekuxilongweni kwempilo yelungu lobufazi. Isetyenziselwa ukubonwa kwe-in vitro qualitative ye-biomarkers ezininzi kwiimfihlo zangasese zabasetyhini, kuquka i-hydrogen peroxide (H₂O₂), i-sialidase (SNA), i-leukocyte esterase (LE), i-proline aminopeptidase (PIP), i-N - i-acetyl - i-β - D - i-glucosaminidase (NAG), i-oxida yexabiso le-pH. I-biomarker nganye idlala indima ebalulekileyo ekuhloleni imiba eyahlukeneyo yempilo yelungu lobufazi:

• Ihydrogen Peroxide (H₂O₂): Isetyenziswa ngokonyango ukumisela ukuba ibhalansi ye-ecology yelungu lobufazi iphazamisekile. I-H₂O₂, phantsi kwesenzo se-peroxidase, iphendula kunye ne-substrate ye-tetramethylbenzidine (TMB) ukuvelisa umkhiqizo onemibala, i-tetramethylbenzidine ene-oxidized, ebonakala i-turquoise okanye eluhlaza okwesibhakabhaka - eluhlaza. Ubunzulu bombala buhambelana ngokuthe ngqo noxinaniso lwe-H₂O₂.
• I-Sialidase (SNA): Isetyenziselwa ukuxilonga i-bacterial vaginosis. I-SNA i-hydrolyzes i-substrate ethile ye-sodium neuraminidase, kunye nemveliso ephumayo, i-bromoindolyl, isabela kunye nomphuhlisi wombala we-nitroblue tetrazolium chloride ukuze ibe ngwevu - blue okanye grey - eluhlaza, kunye nobunzulu bombala obubonisa umsebenzi we-SNA.
• I-Leukocyte Esterase (LE): Inceda ekuxilongeni i-bacterial vaginitis. I-LE i-hydrolyzes i-substrate ethile ye-pyrrolidyl - i-naphthylamide, kunye ne-naphthol ekhutshiweyo - i-4 - i-sulfonic acid isabela ukwenza i-quinone ikhompawundi, ebonakala ngathi i-pink okanye imfusa - epinki, kunye nobukhulu bombala ngokuhambelana nomsebenzi we-LE.
• Iproline Aminopeptidase (PIP): Ikwasetyenziselwa ukuxilonga i-bacterial vaginosis. I-PIP i-hydrolyzes i-substrate ethile ye-proline p - i-nitroaniline, ibonisa umbala ophuzi, kunye nobunzulu bombala buhambelana nomsebenzi we-PIP.
• N – iacetyl – β – D – glucosaminidase (NAG): Isetyenziswe ngokweklinikhi ukuxilonga i-trichomoniasis kunye ne-candidiasis. I-NAG i-hydrolyzes i-substrate ethile ye-N - i-acetyl - β - D - i-glucosaminide, ikhupha i-p - i-nitrophenol, ebonakala imfusa - i-pink okanye i-pink, kwaye ubunzulu bombala bubonisa umsebenzi we-NAG.
• I-Oxidase (OA): Isetyenziselwa ukuxilonga i-vaginitis engachazwanga. I-OA i-oxidizes i-substrate ye-tetramethyl - p - phenylenediamine kwikhompawundi yequinone, ebonakala eluhlaza okwesibhakabhaka, kunye nobunzulu bombala buhambelana nomsebenzi we-OA.
• Ixabiso le-pH: Inceda ukwahlula phakathi kwe-trichomoniasis kunye ne-candidiasis. Ibhloko ye-pH ye-reagent kwiphepha lokuvavanya iqulethe i-substrate yombala we-substrate i-cresol eluhlaza, etshintsha umbala kuluhlu lwe-pH lwe-3.6 - 5.4. Xa i-pH itshintsha ukusuka ku-4.1 ukuya ku-5.1, umbala utshintsha ukusuka kumthubi ukuya kumthubi okhanyayo, oluhlaza okwesibhakabhaka - tyheli, oluhlaza okwesibhakabhaka, noluhlaza okwesibhakabhaka.

Ukubaluleka kweklinikhi kunye neeNzuzo

I-Vaginitis Multitest Kit inikezela ngovavanyo olubanzi lwempilo ye-vaginal, ivumela ababoneleli bezempilo ukuba baxilonge ngokuchanekileyo iintlobo ezahlukeneyo ze-vaginitis, kuquka i-bacterial vaginosis (BV), i-trichomoniasis, i-candidiasis, kunye ne-vaginitis engabonakaliyo, kunye nokuvavanya i-vaginal microecological environment. Ngokubonelela ngolwazi oluneenkcukacha malunga nee-biomarkers ezininzi, inceda ekuqulunqeni izicwangciso zonyango zomntu, ukuphucula ukusebenza konyango, kunye nokunciphisa izinga lokuphindaphinda kosulelo lobufazi.

Case Study 2: Uhambo lukaSarah lokuya ekuBuyiseni

USarah, owasetyhini okhulelweyo oneminyaka engama-28 ubudala, wayefumana ukungakhululeki kunye nokukhutshwa okungaqhelekanga kwilungu lobufazi. Enexhala malunga nefuthe elinokubakho kukukhulelwa kwakhe, uye wavavanywa nge-Vaginitis Multitest Kit. Uvavanyo lubonakalise ukungalingani kwi-microecology yakhe yelungu lobufazi, kunye namanqanaba aphezulu e-sialidase kunye ne-pH engaqhelekanga, ebonisa i-bacterial vaginosis. Umboneleli wakhe wezempilo wakwazi ukumisela ngokukhawuleza unyango olufanelekileyo, olungapheleli nje kuphela iimpawu zakhe kodwa lwanciphisa umngcipheko wokusebenza kwangaphambi kwexesha, eqinisekisa umphumo wokukhulelwa okunempilo.

Ukuthelekiswa kunye neNdlela yokuHlola yeMveli

Iindlela zesiNtu zokuxilonga i-vaginitis, ezifana ne-(white-dicharge microscopy), i-vaginal secretion ye-bacterial culture, uvavanyo lwe-chiza, kunye ne-colposcopy ye-elektroniki, inemida emininzi. I-Microscopy inovakalelo oluguquguqukayo kwaye inokuphosakela usulelo oluthile, ngelixa inkcubeko yebhaktiriya ilixesha-idla, kuthatha iintsuku ezininzi ukufumana iziphumo. Uvavanyo lobuzaza beziyobisi kunye ne-electronic colposcopy nazo zineendleko kwaye zifuna izixhobo ezikhethekileyo kunye nabasebenzi abaqeqeshiweyo. Ngokwahlukileyo, iimveliso zokuxilonga ze-Testsealabs zibonelela ngeziphumo ezikhawulezayo, ukuchaneka okuphezulu, kunye neendleko-ukusebenza, okwenza ukuba zifikeleleke ngakumbi ukuze zisetyenziswe ngokubanzi.

Ukuqukumbela

Ukuqukumbela, i-Candida Albicans / Trichomonas Vaginalis / Gardnerella Vaginalis I-Cassette ye-Antigen Combo Test Cassette kunye ne-Vaginitis Multitest Kit ibonisa inyathelo elibalulekileyo ekuxilongweni kwezifo zangasese. Ezi mveliso zibonelela ngezisombululo ezichanekileyo, ezikhawulezayo, nezibanzi, zijongana nemida yeendlela zokuxilonga zemveli. Ngokubeka phambili impilo yabasetyhini kunye notyalo-mali kwizinto ezintsha, i-Testsealabs yenza impembelelo entle kubomi babasetyhini kwihlabathi liphela, iqinisekisa ukuba bayakwazi ukufikelela kwezona zixhobo zingcono zokuxilonga ukuze kugcinwe impilo yelungu lobufazi. Njengoko inkampani iqhubeka nokukhula kwaye iphuhla, ihleli izibophelele kwinjongo yayo yokuphucula impilo yabasetyhini ngokusika itekhnoloji ye-edge kunye nokhathalelo lwemfesane.