Testsealabs Myoglobin/CK-MB/Troponin ⅠNnwale Combo
Nkọwa dị mkpirikpi:
 Nsonaazụ ngwa ngwa: Lab-nke ziri ezi na nkeji | Nkọwapụta nke ụlọ nyocha: Kwesịrị ntụkwasị obi na ntụkwasị obi |
| Nwalee ebe ọ bụla: Enweghị nleta ụlọ nyocha achọrọ | Ogo enwetara: 13485, CE, Mdsap kwadoro |
| Dị Mfe & Nhazi: Ọ dị mfe iji, nsogbu efu | Ọdịmma kacha mma: nwalee nke ọma n'ụlọ |
Myoglobin (MYO)
Myoglobin (MYO) bụ protein heme-protein a na-ahụkarị na skeletal na akwara obi, yana ịdị arọ molekụla nke 17.8 kDa. Ọ bụ ihe dịka 2% nke protein muscle zuru oke ma na-ahụ maka ibufe oxygen n'ime sel anụ ahụ.
Mgbe mkpụrụ ndụ akwara mebiri emebi, a na-ahapụ myoglobin ngwa ngwa n'ime ọbara n'ihi obere nha ya. Na-esochi ọnwụ anụ ahụ metụtara infarction myocardial (MI), myoglobin bụ otu n'ime akara mbụ na-ebili karịa ọkwa nkịtị:
- Ọ na-abawanye nke ọma n'elu ntọala n'ime awa 2-4 mgbe ọrịa ahụ gasịrị.
- Onu ogugu na awa 9-12.
- Na-alaghachi na ntọala n'ime awa 24-36.
Ọtụtụ akụkọ na-atụ aro enyemaka myoglobin n'ịkwado enweghị infarction myocardial, yana amụma amụma na-adịghị mma ruru 100% nke a na-akọ n'ime oge a kapịrị ọnụ ka akara ngosi malitere.
Creatine Kinase MB (CK-MB)
Creatine kinase MB (CK-MB) bụ enzyme dị na akwara obi, yana ịdị arọ molekụla nke 87.0 kDa. Creatine kinase bụ molekul dimeric e kpụrụ site na subunits abụọ ("M" na "B"), nke jikọtara wee mepụta isoenzymes atọ: CK-MM, CK-BB, na CK-MB. CK-MB bụ isoenzyme kacha etinye aka na metabolism nke anụ ahụ obi.
Na-eso MI, enwere ike ịhụ mwepụta CK-MB n'ime ọbara n'ime awa 3-8 ka akara ngosi malitere:
- Ọnụ kacha elu n'ime awa 9-30.
- Na-alaghachi na ntọala n'ime awa 48-72.
CK-MB bụ otu n'ime ihe nrịbama obi kacha mkpa ma bụrụkwa nke a ma ama dị ka akara ọdịnala maka ịchọpụta MI.
Cardiac Troponin I (cTnI)
Cardiac troponin I (cTnI) bụ protein a na-achọta na akwara obi, yana ịdị arọ nke molekụla nke 22.5 kDa. Ọ bụ akụkụ nke mgbagwoju atọ nke subunit (yana troponin T na troponin C); yana tropomyosin, mgbagwoju a na-ahazi ọrụ ATPase nke nwere mmetụta calcium nke actomyosin n'ime akwara skeletal na obi obi.
Mgbe mmerụ ahụ obi gasịrị, a na-ahapụ troponin I n'ime ọbara 4-6 awa mgbe mgbu malite. Usoro ntọhapụ ya yiri CK-MB, mana ka CK-MB na-alaghachi na nkịtị n'ime awa 72, troponin I na-anọgide na-ebuli elu maka ụbọchị 6-10-na-enye windo nchọpụta ogologo oge maka mmerụ obi.
cTnI nwere nkọwa dị elu maka mmebi myocardial, gosipụtara n'ọnọdụ dị ka oge mgbatị ahụ, ịgba ọsọ marathon, na trauma obi na-adịghị mma. A na-ewepụtakwa ya na ọnọdụ obi na-abụghị nnukwu myocardial infarction (AMI), dị ka angina na-akwụghị ụgwọ, nkụda mmụọ obi, na mmebi ischemic sitere na ịwa ahụ akwara akwara. N'ihi nkọwapụta ya dị elu na uche ya maka anụ ahụ myocardial, troponin I bụ ugbu a bụ ihe kachasị amasị biomarker maka MI.
Myoglobin/CK-MB/Troponin Ⅰ Nnwale ngwakọta
Myoglobin/CK-MB/Troponin Ⅰ Combo Test bụ nyocha dị mfe nke na-eji nchikota nke MYO/CK-MB/cTnI mgbochi mgbochi ụmụ irighiri ihe na ijide reagents iji họrọ MYO, CK-MB, na cTnI n'ime ọbara dum, serum, ma ọ bụ plasma.
