Testsealabs Myoglobin/CK-MB/Troponin ⅠTijaabada Combo
Sharaxaad Gaaban:
 Natiijooyinka degdega ah: Shaybaadhka- Saxsan Daqiiqado gudahood | Saxnaanta Fasalka-Shaybaadhka: Lagu kalsoonaan karo & La aamini karo |
| Tijaabi Meelkasta: Booqashada Shaybaadhka Loo Baahan Yahay | Tayada la xaqiijiyay: 13485, CE, Mdsap Adeeca |
| Fudud & Toosin: fududahay in la isticmaalo, Dhibka eber | Ku habboonaanta ugu dambeysa: Tijaabi si raaxo leh guriga |
Myoglobin (MYO)
Myoglobin (MYO) waa heme-protein sida caadiga ah laga helo lafaha iyo muruqyada wadnaha, oo leh miisaan kelli ah 17.8 kDa. Waxay ka kooban tahay qiyaastii 2% wadarta borotiinka muruqa waxayna mas'uul ka tahay qaadista ogsijiinta gudaha unugyada muruqa.
Marka unugyada muruqa ay dhaawacmaan, myoglobin si degdeg ah ayaa loogu sii daayaa dhiigga sababtoo ah cabbirkiisa oo yar. Ka dib dhimashada unugyada ee la xidhiidha wadnaxanuun myocardial (MI), myoglobin waa mid ka mid ah calaamadaha ugu horreeya ee kor u kaca heerarka caadiga ah:
- Waxay u korodhaa qiyaas ahaan ka sarreeya heerka aasaasiga ah 2-4 saacadood gudahood ka dib fayraska.
- Ugu sarreeya 9-12 saacadood.
- Waxay ku soo noqotaa gundhigga 24-36 saacadood gudahood.
Warbixino dhowr ah ayaa soo jeedinaya in myoglobin cabbiraadda caawinta xaqiijinta maqnaanshaha wadnaxanuun myocardial, oo leh qiyamka saadaalinta xun ee ilaa 100% la soo sheegay waqtiyo gaar ah ka dib bilawga calaamadaha.
Creatine Kinase MB (CK-MB)
Creatine kinase MB (CK-MB) waa enzyme ku jira muruqa wadnaha, oo leh miisaan kelli ah 87.0 kDa. Creatine kinase waa unug-dimeric molecule oo laga sameeyay laba qaybood ("M" iyo "B"), kuwaas oo isku darsaday inay sameeyaan saddex isoenzymes: CK-MM, CK-BB, iyo CK-MB. CK-MB waa isoenzyme inta badan ku lug leh dheef-shiid kiimikaadka unugyada muruqyada wadnaha.
MI ka dib, CK-MB oo lagu sii daayo dhiiga waxaa lagu ogaan karaa 3-8 saacadood gudahooda ka dib bilawga calaamadaha:
- Ugu sarreysa 9-30 saacadood gudahood.
- Waxay ku soo noqotaa gundhigga 48-72 saacadood gudahood.
CK-MB waa mid ka mid ah calaamadaha ugu muhiimsan ee wadnaha waxaana si weyn loogu aqoonsan yahay calaamad dhaqameedka lagu ogaanayo MI.
Wadnaha Troponin I (cTnI)
Cardiac troponin I (cTnI) waa borotiin laga helo muruqa wadnaha, oo leh miisaan kelli ah 22.5 kDa. Waa qayb ka mid ah saddex qaybood oo isku dhafan (oo ay la socdaan troponin T iyo troponin C); oo ay weheliso tropomyosin, kakan ayaa nidaamiya hawlaha ATPase ee xasaasiga ah ee calcium-ka ee actomyosin ee ku jira muruqa qalfoofka ah ee lafaha iyo wadnaha.
Dhaawaca wadnaha ka dib, troponin I ayaa lagu sii daayaa dhiigga 4-6 saacadood ka dib bilawga xanuunka. Nidaamkeeda sii dayntu waxay la mid tahay CK-MB, laakiin halka CK-MB ay ku soo noqoto caadi 72 saacadood gudahood, troponin I ayaa sii kordheysa 6-10 maalmood - taasoo bixisa daaqad dheer oo lagu ogaanayo dhaawaca wadnaha.
cTnI waxay si gaar ah u leedahay dhaawaca myocardial, oo lagu muujiyay xaalado ay ka mid yihiin xilliga qalliinka, orodka marathon ka dambeeya, iyo dhaawac laabta oo aan fiicneyn. Waxa kale oo lagu sii daayaa xaaladaha wadnaha oo aan ka ahayn wadnaxanuun myocardial ba'an (AMI), sida angina aan degganayn, wadno-qabsiga wadnaha, iyo dhaawaca ischemic ee ka yimaada qalliinka halbowlaha wadnaha. Sababo la xiriira gaar ahaaneed iyo dareenka sare ee unugyada myocardial, troponin I hadda waa biomarker-ka ugu doorbiday MI.
Myoglobin/CK-MB/Troponin Ⅰ Imtixaanka Combo
Imtixaanka Myoglobin/CK-MB/Troponin Ⅰ Combo Test waa tijaabo fudud oo adeegsata isku-darka MYO/CK-MB/cTnI walxaha ka-hortagga jidhka ka-hortagga ah iyo soo-celinta reagents si loo ogaado MYO, CK-MB, iyo cTnI ee dhiigga oo dhan, serum, ama balaasmaha.
