Testsealabs CEA Carcinoembryonic Antigen Test
Carcinoembryonic Antigen (CEA)
CEA is a cell surface glycoprotein with an approximate molecular weight of 20,000. Further investigations have shown that CEA can be present in a variety of cancers beyond colorectal cancer, including pancreatic, gastric, lung, and breast cancers, among others. Small amounts have also been demonstrated in secretions from the colonic mucosa.
Persistent elevation in circulating CEA following treatment is strongly indicative of occult metastatic and/or residual disease. A persistently rising CEA value may be associated with progressive malignant disease and a poor therapeutic response. Conversely, a declining CEA value is generally indicative of a favorable prognosis and a good response to treatment.
Measurement of CEA has been shown to be clinically relevant in the follow-up management of patients with colorectal, breast, lung, prostatic, pancreatic, ovarian, and other carcinomas. Follow-up studies of patients with colorectal, breast, and lung carcinomas suggest that the preoperative CEA level has prognostic significance.
CEA testing is not recommended as a screening procedure to detect cancer in the general population; however, the use of the CEA test as an adjunctive test in the prognosis and management of cancer patients is widely accepted.
The minimum detection level is 5 ng/mL.





