Testsealabs Leishmania IgG/IgM Test
Visceral Leishmaniasis (Kala-Azar)
Visceral leishmaniasis, or kala-azar, is a disseminated infection caused by several subspecies of Leishmania donovani.
The World Health Organization (WHO) estimates that the disease affects approximately 12 million people across 88 countries. It is transmitted to humans through the bites of Phlebotomus sandflies, which acquire the infection by feeding on infected animals.
While visceral leishmaniasis is primarily found in low-income countries, it has emerged as the leading opportunistic infection among AIDS patients in southern Europe.
Diagnosis
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Definitive diagnosis: Identification of the L. donovani organism in clinical samples, such as blood, bone marrow, liver, lymph nodes, or spleen.
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Serological detection: Anti-L. donovani IgM is recognized as an excellent marker for acute visceral leishmaniasis. Clinical tests include:
- ELISA
- Fluorescent antibody test
- Direct agglutination test
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Recent advancement: The use of L. donovani-specific proteins in diagnostic tests has significantly improved sensitivity and specificity.
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Leishmania IgG/IgM Test: A simple, visual qualitative test that detects L. donovani antibodies in human whole blood, serum, or plasma. Based on immunochromatography, it provides results within 15 minutes.

