Testsealabs Leptospira IgG/IgM Test

Leptospirosis occurs worldwide and is a common mild to severe health problem for humans and animals, particularly in areas with a hot and humid climate. The natural reservoirs for leptospirosis are rodents as well as a large variety of domesticated mammals. Human infection is caused by leptospirosis, the pathogenic member of the genus of leptospira1,2. The infection is spread via urine from the host animal. After infection, leptospires are present in the blood until they are cleared after 4 to 7 days following the production of anti-leptospirosis antibody, initially of the IgM class. Culture of the blood, urine and cerebrospinal fluid is an effective means of confirming the diagnosis during 1st to 2nd weeks after exposure. Serological detection of anti-leptospirosis antibody is also a common diagnostic method. Tests are available under this category: 1) The microscopic agglutination test (MAT); 2) ELISA; 3) Indirect fluorescent antibody tests (IFATs). However, all above mentioned methods require a sophisticated facility and well-trained technicians. The leptospira IgG/IgM is a simple serological test that utilizes antigens from leptospirosis and detects IgG and IgM antibody to these microorganisms simultaneously. The test can be performed by untrained or minimally skilled personnel, without cumbersome laboratory equipment and the result is available within 15 minutes.