Testsealabs TnI One Step Troponin ⅠTest
Cardiac Troponin I (cTnI)
Cardiac troponin I (cTnI) is a protein found in cardiac muscle with a molecular weight of 22.5 kDa. It is part of a three-subunit complex comprising troponin T and troponin C. Along with tropomyosin, this structural complex forms the main component that regulates the calcium-sensitive ATPase activity of actomyosin in striated skeletal and cardiac muscle.
After cardiac injury occurs, troponin I is released into the blood 4–6 hours after the onset of pain. The release pattern of cTnI is similar to CK-MB, but while CK-MB levels return to normal after 72 hours, troponin I remains elevated for 6–10 days, thus providing a longer window of detection for cardiac injury.
The high specificity of cTnI measurements for the identification of myocardial damage has been demonstrated in conditions such as the perioperative period, after marathon runs, and blunt chest trauma. Cardiac troponin I release has also been documented in cardiac conditions other than acute myocardial infarction (AMI), including unstable angina, congestive heart failure, and ischemic damage due to coronary artery bypass surgery.
Because of its high specificity and sensitivity in myocardial tissue, troponin I has recently become the most preferred biomarker for myocardial infarction.
TnI One Step Troponin I Test
The TnI One Step Troponin I Test is a simple test that utilizes a combination of cTnI antibody-coated particles and capture reagent to selectively detect cTnI in whole blood/serum/plasma. The minimum detection level is 0.5 ng/mL.

