Testsealabs Vibro Cholerae O139(VC O139)and O1(VC O1)Combo Test
Short Description:
Vibro Cholerae O139 (VC O139) and O1 (VC O1) Combo Test is a rapid and convenient immunochromatographic assay for the qualitative detection of VC O139 and VC O1 in human fecal samples/environmental water.
 Rapid Results: Lab-Accurate in Minutes |
Lab-Grade Precision: Reliable & Trustworthy |
| Test Anywhere: No Lab Visit Required |
Certified Quality: 13485, CE, Mdsap Compliant |
| Simple & Streamlined: Easy-to-Use, Zero Hassle |
Ultimate Convenience: Test Comfortably at Home |
Vibrios are gram-negative, highly motile curved rods with a single polar flagellum.
Until 1992, cholera was caused by only two serotypes (Inaba and Ogawa) and two biotypes (classical and El Tor) of toxigenic Vibrio cholerae O1. These organisms may be identified by:
- Biochemical tests and bacterial culture on selective media;
- Agglutination in O group 1 specific antiserum (directed against the lipopolysaccharide component of the cell wall);
- Demonstration of their enterotoxigenicity with PCR.
Vibrio cholerae O139 is a new strain of cholera first isolated in 1993. It appears to have been derived from the El Tor biotype, retaining the epidemic potential of O1 strains and producing the same cholera enterotoxin, though it has lost the characteristic O1 somatic antigen.
This serovar is identified by:
- Absence of agglutination in O group 1 specific antiserum;
- Agglutination in O group 139 specific antiserum;
- Presence of a polysaccharide capsule.
V. cholerae O139 strains undergo rapid genetic changes, which facilitates the bacteria gaining resistance to antibiotics. Furthermore, previous infections with serogroup O1 do not provide immunity against O139. It is anticipated that the extent and rapidity of the spread of disease caused by O139 is most likely to trigger the next cholera pandemic worldwide.
V. cholerae causes diarrhea via colonization in the small intestine and production of a potent cholera toxin. Given the clinical and epidemiological severity, it is critical to determine the presence of V. cholerae as quickly as possible in clinical specimens, water, and food. This allows public health authorities to implement appropriate monitoring and effective preventive measures.
